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Proteins, including enzymes, are produced in the cytoplasm and in the rough endoplasmic reticulum. All proteins in cells are synthesized at ribosomes.

Almost all enzymes are proteins, but some RNA molecules act as catalysts too.

When protein synthesis begins, a ribosome is free in the cytoplasm, but a little way into the process, the cell inspects the amino acid sequence of the completed part of the polypeptide chain. Depending on this sequence, the ribosome may be moved to the rough endoplasmic reticulum.

So some proteins are finished in the lumen (cavity) of the rough endoplasmic reticulum, and others are entirely synthesized in the cytoplasm.

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16y ago

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