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  • Replication and transcription involves a parental DNA strand that is the foundation on which the products are built on.
  • Replication and transcription both have initiation step which involve the breakage of the parental DNA strand.
  • Replication and transcription both have specific proteins that keep the polymerase molecule attached to the parental DNA strand. There are elongation factors for transcription and sliding clamp for replication.
  • Both processes use DNA topoisomerases to relieve supercoiling.
  • Both processes only proceed in the 5' to 3' direction.
  • Replication and transcription both involve the addition of specific 3' endings. In replication, it is the addition of the GGGTTA sequence by telomerase. In transcription, it is the addition of the poly-A tail.
  • Both processes used nucleotides as the language on which the daughter strands come from.
  • Replication and transcription involve the hydrolysis of a phosphodiester bonds to begin their process.
  • Both processes take place in the nucleus.
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13y ago
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14y ago

One of the way in which these both process are similar is that in both these process DNA is used as template. In replication, DNA is synthesised on DNA template and in transcription the DNA template is used for the synthesis of RNA molecule.

But the most striking feature is the mechanism of action of DNA and RNA polymerase. both have Mg2+ as cofactor. both these enzymes add one nucleotide at a time. Moreover, both the enzymes forms phosphodiester bond between the Phosphate group and the 3' Carbon of pentose sugar.

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13y ago

Transcription is similar to DNA Replication

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12y ago

they both use a DNA template to produce a new strand both build polynucleotide strands

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14y ago

Replication

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Q: The process of transcription is similar to the process of DNA?
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