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What are the different types of sickle cell disease and how do they differ from each other?
There are several types of sickle cell disease, including sickle cell anemia, sickle beta thalassemia, and sickle cell-hemoglobin C disease. These types differ based on the specific genetic mutations that affect the hemoglobin protein in red blood cells. Sickle cell anemia is the most common and severe form, where individuals have two copies of the sickle cell gene. Sickle beta thalassemia and sickle cell-hemoglobin C disease are milder forms that result from different combinations of genetic mutations. Symptoms and complications can vary among the different types of sickle cell disease.
What else can I help you with?
What is sicle cell?
I think you mean sickle cell diseaase. Here is some more information for you that will answer your question better than I can: http://en.wikipedia.org/wiki/Sickle_cell_disease In short, sickle cell disease is a blood disorder of the red blood cells. Basically, the red blood cells have an abnormal, rigid, sickle shape (hence the name sickle cell disease).
Why do some people have different shaped red blood cells?
Some people have diseases, such as Sickle Cell Anemia. The disease makes a person's red blood cells in the shape of a sickle, hence the name, "Sickle" Cell Anemia. A normal person's red blood cell shape is round as opposed to the diseased person's red blood cell. It depends on the type of disease the person has. Some are round, some sickle shape, and others raisen-like (drained).
Sickle cells cause what type of genetic blood disease?
Sickle cell anaemia is caused by a genetic mutation that affects the normal development of haemoglobin. A genetic mutation is a permanent alteration in the normal pattern of DNA that makes up genes. Genes consist of coiled strands of DNA, and each cell contains the same genetic material.
How can mutations in different genes contribute to the development of a single disease?
Mutations in different genes can contribute to the development of a single disease by affecting various biological pathways or processes that are involved in the disease. These mutations can interact with each other or with environmental factors to disrupt normal cellular functions, leading to the manifestation of the disease.
What is genetic variation?
My answer off the top of my head is that the male sperm cell carries half the chromosomes (they contain all your genetic information) and the female egg carries the other half. When they join to create a zygote, you will inherit those chromosomes. There are different types of alleles (this is a different type of the same gene). One type is Homozygous where, in the example of the allele that lets you roll your tongue, is Rr. A heterozygous is RR or rr. You can inherit any of these. However, if you should inherit the rr gene, then you will not be able to roll your tongue. You will still carry the gene. So if you create a child then he/she can become a carrier for the gene (Rr). They can then create a person who can roll their tongue if the other person can or is a carrier. There are special tables to determine if your child will have it or not. A good example of a carrier disease is Sickle-Cell Disease. Normal red blood cells are shaped like o's. Sickle-Cell infected people's red blood cell's are shaped like crescent moons. A carrier or someone infected with Sickle-Cell Disease are immune to Malaria because Malaria cannot cope with the mutated cells of the subject. This is why a lot of African people have Sickle-Cell disease.
What are other names for sickle cell anemia?
Hemoglobin SS disease (Hb SS)
Is sickle cell anemia a disease?
I don't know what a communitive disease is, and neither does the dictionary, but sickle cell anemia is an inherited abnormality. I hope that helps.If you are asking if sickle cell is a disease in which you can catch from other people. The answer is No. It is an inherited Blood disorder.
Can you have a seizure when you have sickle sell anemia?
sicklers are as any normal person so they can get seizure not because sickle cell disease , but because any other disease
Which race is more commonly inherited with sickle cell disease?
Sickle cell disease is more common among blacks than among people of other races.
What is description of sickle cell disease?
Sickle cell disease is commonly referred to as sickle cell anaemia, or drepanocytosis. The blood cells that are normally round, flat, disks, are instead shaped in a tiny curved sickle shape, hence the name. The other major difference between the blood cells is the sickle shape is dramatically more rigid than healthy cells. This major difference can lead to problems clotting or blocking blood vessels in the body. There are a few distinct versions of having sickle cell disease, that are mostly distinct by the different genes that the person is carrying.
Can sickle cell be known before birth?
Yes! If both parents have the sickle cell disease, the child will have sickle cell. Otherwise, you can Google it or bing it to see other ways.
What are abnormal crescent shaped BLOOD cell?
Abnormal crescent-shaped blood cells are known as sickle cells, which are characteristic of sickle cell disease. This genetic condition causes red blood cells to become rigid and curved, leading to blockages in blood vessels and reduced oxygen delivery to tissues. Sickle cell disease can result in pain, organ damage, and other serious complications.
What other celebrities have sickle cell disease?
tiki barber the rapper prodigy and many others
Top 10 questions asked about sickle cell?
What is sickle cell disease?Sickle cell disease is an inherited disorder that affects red blood cells. People with sickle cell disease have red blood cells that become hard and pointed instead of soft and round. Sickle cells cause anemia, pain and many other problems.Top2) What is sickle cell trait?If you have sickle cell trait, you have inherited the gene for sickle cell disease. Sickle cell trait does not turn into sickle cell disease. If someone has sickle cell trait and his partner has sickle cell trait they may produce a child with sickle cell disease. There are about 2.5 million people in America with sickle cell trait.Top3) If sickle cell trait is not an illness, why are people tested?Babies are tested to see if they have sickle cell disease. Teens and adults are tested mainly to see if they can have a baby with the disease.Top4) What medical problems are caused by sickle cell disease?Lung tissue damage, pain episodes and stroke. The blockage of blood flow caused by sickled cells also causes damage to most organs including the spleen, kidneys and liver.Top5) How many people have sickle cell disease?Sickle cell disease is a global health problem. In the United States it is estimated that over 70,000 people have sickle cell disease. About 1,000 babies are born with the disease each year in America.Top6) How long does a person with sickle cell disease live?The average life expectancy in America has improved. It is now in the mid 40 years of age range.Top7) Are people of African descent the only group affected?No. It is also present in Portuguese, Spanish, French Corsicans, Sardinians, Sicilians, mainland Italians, Greeks, Turks and Cypriots. Sickle cell disease also appears in Middle Eastern countries and Asia.Top8) Is there a cure?There is no universal cure for sickle cell disease. Research in gene therapy, the ultimate universal cure, is currently underway.Top9) What are some promising treatment developments?The use of hydroxyurea has shown promising results on some adult sickle cell patients. It reduces the frequency of severe pain, acute chest syndrome and the need for blood transfusions.Top10) Can people with sickle cell disease live a productive life?Yes. But like all patients with chronic disease, sickle cell patients are best managed in a comprehensive multi-disciplinary program of care and a strong extended support system.
Is sickle cell anemia a communicable or noncommunicable?
I don't know what a communitive disease is, and neither does the dictionary, but sickle cell anemia is an inherited abnormality. I hope that helps.If you are asking if sickle cell is a disease in which you can catch from other people. The answer is No. It is an inherited Blood disorder.
Can child be born with sickle cell if one parent is sickle cell carrier and another is normal?
A child has to receive the gene from both parents to heve sickle cell anemia. if only one parent passes on the gene, then the child will have sickle cell trait, but no symptoms of sickle cell anemia.
What other group besides blacks does sickle cell affect?
Sickle cell disease predominantly affects individuals of African, Mediterranean, Middle Eastern, and Indian descent. It can also affect people from other regions with a history of malaria, as the sickle cell trait provides some protection against the disease.
