When two incompatible blood cells mix and come into contact with each other, a reaction called agglutination occurs. This can lead to clumping of the blood cells, which can block blood vessels and cause serious health complications.
When incompatible blood types are mixed, the recipient's immune system may produce antibodies that attack the transfused red blood cells. This can lead to the breakdown of red blood cells, known as hemolysis. Hemolysis can cause potential complications such as jaundice, kidney failure, and even death if not addressed promptly. In severe cases, a condition called hemolytic transfusion reaction can occur, which is a medical emergency requiring immediate intervention.
Antigens determine a person's blood type. These antigens are present on the surface of red blood cells and stimulate the immune system to produce antibodies against incompatible blood types.
After old red blood cells rupture, the fragments are broken down by the body's immune system and recycled for the production of new red blood cells.
The type B blood has an antigen on the red cells identifying them as B type cells. The type A blood of the recipient contains antibodies that bind to B type antigens. These antibodies will cause the red cells of the blood in the transfusion to stick together forming solid lumps in the blood, preventing it from flowing.
Worn out red blood cells are removed by the spleen, liver, and bone marrow. The cells are broken down and their components are recycled or excreted from the body. This process helps maintain the appropriate level of healthy red blood cells in circulation.
On the surface of red blood cells Take A type blood, for instance. It has antigens against B type blood contact on its cell surface.
Agglutunation
PYROGEN
When incompatible blood is transfused, the recipient's immune system recognizes the foreign red blood cells (RBCs) as threats and produces antibodies against them. This leads to agglutination, where the antibodies bind to the foreign RBCs, causing them to clump together. The agglutinated cells can then be destroyed by the immune system, often resulting in hemolysis, which can lead to serious complications such as anemia, kidney failure, and shock.
The clumping of red blood cells, known as agglutination, occurs due to the immune response involving antibodies. When incompatible blood types are mixed, the antibodies present in the recipient's serum recognize the foreign antigens on the transfused red blood cells. This binding triggers the aggregation of the cells, leading to clumping. The immune system's attempt to eliminate these foreign cells can result in serious complications.
Materials needed by the cells move from the blood into the cells, and waste materials move from the cells into the blood.
Polycythemia or an increase in red blood cells
Blood clumping, or agglutination, occurs when blood cells clump together due to the presence of antibodies that react with antigens on the surface of the cells. This can happen during incompatible blood transfusions or in certain autoimmune diseases where the immune system mistakenly targets its own blood cells.
They die
Erythropoiesis (making red blood cells) and the synthesis of other blood cells.
different types of blood cells are formed
What happens to antibodies when they destroy microbes