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The basolateral membrane in epithelial cells helps transport molecules into and out of the cell. It plays a key role in regulating the movement of substances between the cell and its surroundings.

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7mo ago

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What does basolateral do?

The basolateral membrane is a crucial component of epithelial cells, located on the side of the cell facing the underlying tissue and blood vessels. It plays a key role in the transport of nutrients, ions, and water between the epithelial cells and the bloodstream, facilitating absorption and secretion processes. This membrane is also involved in cell signaling and maintaining the electrochemical gradients essential for various cellular functions.


What is a basolateral membrane transporter?

A basolateral membrane transporter is a type of protein located in the basolateral membrane of epithelial cells, which faces the bloodstream or interstitial fluid. These transporters are responsible for facilitating the movement of ions, nutrients, and other molecules from the interior of the cell into the surrounding extracellular environment or vice versa. They play a crucial role in maintaining homeostasis and regulating the absorption of substances in various tissues, such as the intestines and kidneys. Examples include sodium-potassium pumps and glucose transporters.


Epithelial membranes is known as the blood-facing membrane?

The blood-facing membrane of epithelial cells is known as the endothelium. It lines blood vessels and forms a barrier between the blood and surrounding tissues. The endothelium is crucial for regulating the transportation of substances in and out of the bloodstream.


What does aldosterone increase in the basolateral membrane?

Basolateral Na+ K+ ATPase pumps


How do glucose molecules cross a plasma membrane on the apical side of epithelial cells?

Glucose molecules cross the plasma membrane on the apical side of epithelial cells through facilitated diffusion using glucose transporters such as GLUT1 and GLUT2. These transporter proteins help the glucose molecules move down their concentration gradient into the cell.


What is the function of epitheliam tissue?

Functions of epithelial cells include secretion, selective absorption, protection, transcellular transport and detection of sensation. As a result, they commonly present extensive apical-basolateral polarity (e.g. different membrane proteins expressed) and specialization.


How do carrier proteins facilitate the passive transport of molecules across a membrane?

Carrier proteins facilitate the passive transport of molecules across a membrane by binding to specific molecules on one side of the membrane and changing shape to transport the molecules across to the other side. This process does not require energy and is driven by the concentration gradient of the molecules.


Does facilitated diffusion require energy to transport molecules across the cell membrane?

Facilitated diffusion does not require energy to transport molecules across the cell membrane.


Does passive transport require ATP for the movement of molecules across the cell membrane?

No, passive transport does not require ATP for the movement of molecules across the cell membrane.


What biomolecule helps transport molecules across the membrane?

proteins


Absorption of glucose from the gut lumen depends on?

the sodium-potassium pump in the basolateral membrane of the epithelial cell, cotransporter proteins in the apical membrane of the epithelial cell, and higher sodium ion concentration in the lumen than in the epithelial.


Does facilitated transport require energy for the movement of molecules across the cell membrane?

Yes, facilitated transport does require energy for the movement of molecules across the cell membrane.