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The partial mole karyotype is important in diagnosing and managing gestational trophoblastic disease because it helps identify genetic abnormalities in the placental tissue. This information can guide treatment decisions and prognosis for the patient.

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What has the author Donald Peter Goldstein written?

Donald Peter Goldstein has written: 'Gestational trophoblastic neoplasms' -- subject(s): Diagnosis, Drug therapy, Trophoblastic Tumor, Trophoblastic tumors


Gestational trophoblastic disease?

DefinitionGestational trophoblastic disease (GTD) refers to a group of abnormalities in which tumors grow inside a woman's uterus (womb). The abnormal cells start in the tissue that would normally become the placenta, the organ that develops during pregnancy to feed the fetus.A baby may or may not develop during these types of pregnancies.There are several types of GTD. See the specific articles for more information:Choriocarcinoma(a type of cancer)Hydatiform mole(also called a molar pregnancy)ReferencesGoldstein DP, Berkowitz RS. Gestational trophoblastic disease. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds. Abeloff'sClinical Oncology. 4th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 94.Kavanagh JJ, Gershenson DM. Gestational Trophoblastic Disease: Hydatidiform Mole, Nonmetastatic and Metastatic Gestational Trophoblastic Tumor: Diagnosis and Management. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 35.Soper J, Creasman JT. Gestational trophoblastic disease. In: Disaia PJ, Creasman WT, eds. Clinical Gynecologic Oncology. 7th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 7.


If hcg levels are high and seen a blood clot?

High hCG levels can indicate pregnancy, but they may also be associated with certain medical conditions such as molar pregnancy or trophoblastic disease. The presence of a blood clot could be a sign of a potential complication, such as a miscarriage or an ectopic pregnancy. It's crucial to consult a healthcare professional for an accurate diagnosis and appropriate management based on individual circumstances.


Choriocarcinoma?

DefinitionChoriocarcinoma is a quick-growing form of cancer that occurs in a woman's uterus (womb). The abnormal cells start in the tissue that would normally become the placenta, the organ that develops during pregnancy to feed the fetus.Choriocarcinoma is a type of gestational trophoblastic disease.See also:Gestational trophoblastic diseaseHydatiform moleAlternative NamesChorioblastoma; Trophoblastic tumor; Chorioepithelioma; Gestational trophoblastic neoplasiaCauses, incidence, and risk factorsChoriocarcinoma is an uncommon, but very often curable cancer associated with pregnancy. A baby may or may not develop in these types of pregnancy.The cancer may develop after a normal pregnancy; however, it is most often associated with a complete hydatidiform mole. The abnormal tissue from the mole can continue to grow even after it is removed and can turn into cancer. About half of all women with a choriocarcinoma had a hydatidiform mole, or molar pregnancy.Choriocarcinomas may also occur after an abortion, ectopic pregnancy, or genital tumor.SymptomsA possible symptom is continued vaginal bleeding in a woman with a recent history of hydatidiform mole, abortion, or pregnancy.Additional symptoms may include:Irregular vaginal bleedingOvarian cystsUneven swelling of the uterusPainSigns and testsA pregnancy test will be positive even when you are not pregnant. Pregnancy hormone (HCG) levels will be persistently high.A pelvic examination may reveal continued uterine swelling or a tumor.Blood tests that may be done include:Quantitative serum HCGComplete blood countKidney function testsLiver function testsImaging tests that may be done include:CT scanMRITreatmentAfter an initial diagnosis, a careful history and examination are done to make sure the cancer has not spread to other organs. Chemotherapy is the main type of treatment.A hysterectomyand radiation therapy are rarely needed.Support GroupsFor additional information, see cancer resources.Expectations (prognosis)Most women whose cancer has not spread can be cured and will maintain reproductive function.The condition is harder to cure if the cancer has spread and one of more of the following events occur:Disease has spread to the liver or brainPregnancy hormone (HCG) level is greater than 40,000 mIU/mL at the time treatment beginsCancer returns after having chemotherapy in the pastSymptoms or pregnancy occurred for more than 4 months before treatment beganChoriocarcinoma occurred after a pregnancy that resulted in the birth of a childMany women (about 70%) who initially have a poor outlook go into remission (a disease-free state).ComplicationsA choriocarcinoma may come back after treatment, usually within several months but possibly as late as 3 years. Complications associated with chemotherapy can also occur.Calling your health care providerCall for an appointment with your health care provider if symptoms arise within 1 year after hydatidiform mole, abortion (including miscarriage), or term pregnancy.PreventionCareful monitoring after the removal of hydatidiform mole or termination of pregnancy can lead to early diagnosis of a choriocarcinoma, which improves outcome.ReferencesGoldstein DP, Berkowitz RS. Gestational trophoblastic disease. In: Abeloff MD, Armitage JO, Niederhuber JE, Kastan MB, McKenna WG, eds. Abeloff's Clinical Oncology. 4th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2008:chap 94.Kavanagh JJ, Gershenson DM. Gestational trophoblastic disease: hydatidiform mole, nonmetastatic and metastatic gestational trophoblastic tumor: diagnosis and management. In: Katz VL, Lentz GM, Lobo RA, Gershenson DM. Comprehensive Gynecology. 5th ed. Philadelphia, Pa: Mosby Elsevier; 2007:chap 35.Soper J, Creasman JT. Gestational trophoblastic disease. In: Disaia PJ, Creasman WT, eds. Clinical Gynecologic Oncology. 7th ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 7.


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What sugars can you eat if you have gestational diabetes?

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