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adv..... heat fixing inactivates enzymes that would normally disrupt cell morphology and structure during staining and observation.
dis....... if not done well much of the specimen can be destroyed in heat fixing.
Wiki User
∙ 13y ago
Wiki User
∙ 11y agoHeat fixing kills the specimen. Also heat fixing cannot be used in capsular staining as the heat destroys the capsule(glycocalyx). Air dying contaminates the smear.
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