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What are three categories of genes that when mutated can lead to tumor formation?
Wiki User
∙ 10y ago
· 1) Genes involved in cell division
· 2) Oncogenes
o Dominant-acting stimulatory genes
o Normally low levels or expression is turned off
o Mutation causes increased/hyper expression
· 3) Tumour suppressor genes
o Recessive-acting genes
o Normally expressed to inhibit cell division
o Mutation causes defects in product or no expression
Wiki User
∙ 10y ago
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