What causes haemophilia?

Answer 1

Hemophilia is a disorder that is defined by the absence of one or more proteins required for blood clotting. If a person with hemophilia is injured, the bleeding is prolonged because a clot forms very slowly. This can lead to massive internal as well as external bleeding from serious injuries.

Answer 2

If you have inherited hemophilia, you're born with the condition. It's caused by a defect in one of the genes that determine how the body makes blood clotting factor VIII or IX. These genes are located on the X chromosomes (KRO-muh-somz).

Chromosomes come in pairs. Females have two X chromosomes, while males have one X and one Y chromosome. Only the X chromosome carries the genes related to clotting factors.

A male who has the abnormal gene on his X chromosome will have hemophilia. A female must have the abnormal gene on both of her X chromosomes to have hemophilia; this is very rare.

A female is a "carrier" of hemophilia if she has the abnormal gene on one of herX chromosomes. Even though she doesn't have the condition, she can pass the gene on to her children.

Hemophilia also can be acquired. In these cases (however rare) things such as liver damage or medications cause the hemophilia, not the genetics. Again this form of hemophilia can not be transmitted to others.

Answer 3

Hemophilia is caused by genetic mutations that affect the clotting factors in the blood. It is most commonly inherited from parents who carry the faulty gene. Hemophilia primarily affects males, as it is an X-linked recessive disorder.

Answer 4

Usually genetically, meaning you have to be born with it to have it. But it can also be acquired if your body forms antibodies to the clotting factors in your bloodstream.

Answer 5

due to the lack of protein that is needed for blood clotting

Answer 6

Hemophilia is caused by a genetic mutation on the X chromosome. Because males have only one X chromosome, hemophilia is typically found more commonly in men than in women.