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Code 96 donors have a particular combination of antigens that make their red cells rare. An antigen is a type of protein on the outer surface of the red blood cell. When a patient receives a transfusion of blood carrying the same antigens as his or her own blood, the donor red cells are "welcomed" into the body because they do not recognize the transfused cells are foreign. If the patient does not have the same antigens, they may develop antibodies to the antigens and their body may reject or react with future blood transfused with these antigens. Patients who are transfused very often can easily form antibodies (immune responses) to some red cell antigens. Once antibodies from, these patients require very precisely matched transfusions to prevent transfusion reactions and production of more antibodies. Some of the conditions that require

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