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Histones are proteins that organize DNA in the chromatin of eukaryotes (cells that have membrane enclosed nuclei). Acetylation means the introduction of acetyl group to a molecule. In essence, Histone Acetylation removes the positive charge on the histones which, in turn, causes a decrease in the interaction with negatively charged phosphates in DNA.
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In eukaryotes what is active transcription generally associated with?
Both euchromatin and histone acetylation.
What is DNA wrapped around in a nucleosome?
They're called histone proteins. There are 8histones proteins in which a loop of DNA wraps around twice. Then another histone protein called the H1 linker binds them together.
What is histone core?
A Histone Core is a group of Histone Proteins, mainly used in eukaryotes to package DNA strands into Nucleosomes. (Think of it like a spool for the DNA to wrap around, to be easily stored on a shelf)
What is composed of DNA and proteins?
chromatids/chromatin.
Eukaryotic chromosomes contain both DNA and protein tightly packed together to form a substance called?
The complex of both histone and non-histone chromosomal proteins and DNA is known as chromatin.
What are genomic imprinting DNA methylation and histone acetylation examples of?
Epigenetic Phenomena.
In eukaryotes what is active transcription generally associated with?
Both euchromatin and histone acetylation.
How do DNA methylation and histone acetylation affect chromatin structure and the regulation of transcription?
When chromatin is tightly compacted and dense, it's called Heterochromatin. When chromatin is loosely packed, its called Euchromatin. Euchromatin is easily accessible to transcription enzymes, while herterochromatin makes transcription impossible because the enzymes cannot access the DNA. Therefore, a gene within heterochromatin cannot be expressed. Also, look up how histone modifications such as histone acetylation affect gene expression.
What is role of histone phosphorylation?
Since phosphate groups have a negative charge, adding them to histone tails neutralizes them and probably reduces their affinity for DNA. It might contribute to transcription because it stimulates histone acetyltransferases which cause histone acetylation and enhance transcription.
What is acetylation and which chemicals are commonly involved?
Acetylation describes the process of an introduction of an acetyl functional group into chemical compounds. Chemicals that are commonly involved are succinic acid.
What are the sources of histone binding protein RbAp48?
what are the sources of histone binding protien RbAp48
What are histone?
HistonesHistones are proteins that aid in the organization of DNA into chromosomes. There are four types of histones found in chromatin: H2A, H2B, H3, and H4. Two of each histone comprise a protein core, a nucleosome, which DNA wraps around twice. What results is a "bead on a string" model in which the nucleosomes are the beads and the linker DNA binds them together. Another characteristic of histones are the protein tails that extend outward from the "bead." The tails and the degree of their acetylation is an important factor in gene expression. See related links and images below.
How many different types of histone subunits are present in a nucleosome?
the number of histone subunits in a nucleosome is?
What is DNA wrapped around in a nucleosome?
They're called histone proteins. There are 8histones proteins in which a loop of DNA wraps around twice. Then another histone protein called the H1 linker binds them together.
What are nonhistones?
histone are nonprotienous
Does ATP contain histone?
No, it does not.
What is histone core?
A Histone Core is a group of Histone Proteins, mainly used in eukaryotes to package DNA strands into Nucleosomes. (Think of it like a spool for the DNA to wrap around, to be easily stored on a shelf)
