Hypertension represents a common and powerful predisposing factor for cardiovascular disease or events and renal failure. Approximately 90% of patients with end-stage renal disease (ESRD) have a history of hypertension. High blood pressure may initiate renal damage and also increase the rate of progression of renal insufficiency. Persistent high blood pressure represents the early trigger mechanism for renal disease.
The final pathway is represented by progressive sclerosis of glomeruli (Vascular part of nephron). A main role is played by transforming growth factor 1 (TGF1), a multifunctional cytokine that regulates cell growth, differentiation, matrix production, blocks matrix degradation, inducing fibrosis in many tissues, including kidney, blood vessels, lung and heart. High circulating levels of TGF1 can mediate renal fibrosis and loss of function.
list the parts of the nephron and describe the function of each part
the cortical nephron is another type of nephron which has shorter loop of henle extended in medulla region. it has no proper function but it works like as ultra filtration etc as juxta medullary nephron perform but juxta medullary has proper function.
The blood pressure in these capillaries is relatively high, so pressure filtration occurs. The blood's plasma and small waste materials and chemicals (the contents of the closet) are pushed out of the blood into the nephron, leaving behind larger proteins, nutrients, and blood cells.
The juxtaglomerular apparatus is a microscopic structure in the kidney, which regulates the function of each nephron. The juxtaglomerular apparatus is named for its proximity to the glomerulus: it is found between the vascular pole of the renal corpuscle and the returning thick ascending limb of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells
The loop Henle, part of the function unit in the kidnay called the Nephron
list the parts of the nephron and describe the function of each part
list the parts of the nephron and describe the function of each part
Nephron
the cortical nephron is another type of nephron which has shorter loop of henle extended in medulla region. it has no proper function but it works like as ultra filtration etc as juxta medullary nephron perform but juxta medullary has proper function.
The nephron is a functional unit of the kidney which filters the blood and maintains the body's internal homeostasis.
The nephron is a functional unit of the kidney which filters the blood and maintains the body's internal homeostasis.
If your blood pressure is too high, as in the case of someone with hypertension, the glomerulus of the nephron can burst rendering that nephron useless. Without a glomerulus, the nephron cannot achieve pressure filtration, which is one of the main functions of the kidney.
Yes
ADH increases water reabsorption in the collecting ducts Aldosterone works on the distal convoluted tubule and leads to increased blood pressure.
nephron, each kidney has atleast 1 million
Hydrogen ion excretion is the result of standard kidney (nephron) function, when processing fluids in the body. This is done at the bottom of the kidneys.
Nephrons have the same function in all kidneys. They allow the excretion of water, sodium and urea to form urine. They serve the function of removing waste chemicals such as metabolites and drugs from the body. Excretion of sodium and water is also important in the nephron as it allows the kidney to control blood pressure and blood volume.