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A binding site is the outer part of the protein that is folded into a unique shape. It has to have this certain shape, otherwise the enzyme and substrate will not fit together. This is called a "lock and key" mechanism.

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Q: What is a binding site and why does it have a specific shape?
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What is a binding site?

The binding site is where a specific binding molecule and a specific receptor protein can combine. This combination can only occur at the binding site. All in the 9th grade text book


Difference between active site and binding site?

Binding site is anywhere which something (such as a protein) can bind to. An example would be the upper flanking regions which contain binding sites thattranscription factors bond with during transcription. The active site is more specific to enzymes and refers to the site where the enzyme functions. It is the specific contours of this active site which give the enzyme its specific function (see how enzymes are substrate specific).


What blocks enzyme activity by binding to allosteric site of an enzyme causing the enzyme's active site to change shape?

An allosteric inhibitor stops enzyme activity by binding to an allosteric site and causing the conformation of the enzyme to change.


Difference between allosteric and covalent modulation?

The 2 mechanisms to alter protein shape are allosteric and covalent modulation. Allosteric: If the protein contains 2 binding sites, the noncovalent binding of a ligand to one site can alter the shape & characteristics of the other site. -One binding site on an allosteric protein, the functional site, carries out the proteins physiological functions. -The other binding site is the regulatory site, and the ligand that binds to it is called the modulator molecule because it changes the shape! Covalent: Covalent bonding of charged chemical groups to some of the proteins side chains changes the shape and characteristics of the protein. Usually a phosphate group is covalently bonded, in the reaction called phosphorylation.


This is a specific region of an enzyme where a substrate binds and the chemical reaction occurs?

it i called an active site


Which is a correct association of protein types?

Receptor proteins- have a binding site for a specific molecule


How is it possible that trypsin can catalyse many reactions?

enzymes act by having a complementary active site to the shape of a certain molecule, binding to it then reacting it or hydrolyzing it of whatever. trypsins active site happens to be less specific and can fit a wide range of proteins in.


What are three techniques used to determine the specific DNA binding site of a DNA-binding protein?

Well to determine the binding site of the protein, you would need to determine the structure of the protein. one of the techniques used is NMR (nuclear magnetic resonance..i think lol).


What is antigen binding?

Antigen binding is a region on an antibody that binds to antigens. Antigen binding is composed of one constant and one variable domain of each of the heavy and the light chain, and these domains shape the antigen binding site at the amino terminal end of the monomer.


Why are enzymes so specific in their actions?

The enzymes are so specific to their action because they have substrate binding site which has three dimensional configuration which binds to the complementarity three dimensional substrate molecule and hence the enzymes are specific in binding the site and their action In case if the structural configuration of the enzyme changes the substrate is unable to bind at that site and the reaction does not take place


What characteristics of enzymes makes them specific for substrate?

shape of their active site make them specific for the substrates


Is an enhancer is a sequence of nucleotides that when activated by specific signal proteins aids in shielding the RNA polymerase binding site of a specific gene?

False: its An Repressor not an enhancer