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What is a non synonymous polymorphism?

Updated: 4/28/2022
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Substitutions that result in amino acid replacements are said to be nonsynonymous while substitutions that do not cause an amino acid replacement (such as a GGG to GGC change - both codons still encode glycine) are said to be synonymous substitutions

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Q: What is a non synonymous polymorphism?
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What is a synonymous polymorphism?

A synonymous polymorphism is where a mutation alters the base in the DNA sequence but doesn't alter the amino acid encoded (due to the redundancy of the genetic code). Typically, for it to be classified as a polymorphism (as opposed to a mutation) it must occur in greater than 1% of the population.


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Does non crystalline material possess the concept of allotropy or polymorphism?

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Are expanded family and extended family synonymous?

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