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Glucose to glucose 6-phosphate. Irreversible. Hexokinase/gluckokinase. Requires ATP and Mg2?
The conversion of glucose to glucose 6-phosphate catalyzed by hexokinase/glucokinase is an irreversible reaction that traps glucose within the cell. This process consumes one molecule of ATP and requires Mg2+ as a cofactor. Hexokinase has a high affinity for glucose and is present in most tissues, while glucokinase is found primarily in the liver and pancreas with a lower affinity for glucose.
What would happen if an organism lacked hexokinase?
If an organism lacked hexokinase, it would be unable to phosphorylate glucose to glucose-6-phosphate, which is the first step in glucose metabolism. This would impair the organism's ability to utilize glucose for energy production.
Why ATP is needed not GTP for hexokinase reaction?
ATP is used in the hexokinase reaction because it acts as the source of phosphate for the phosphorylation of glucose to form glucose-6-phosphate. Hexokinase specifically recognizes and phosphorylates glucose, and it has a higher affinity for ATP compared to GTP. Therefore, ATP is the preferred energy source for this reaction.
What are the irreversible steps in glycolysis and how do they contribute to the overall regulation of the pathway?
The irreversible steps in glycolysis are catalyzed by the enzymes hexokinase, phosphofructokinase, and pyruvate kinase. These steps help regulate the pathway by controlling the flow of glucose through glycolysis. Hexokinase converts glucose to glucose-6-phosphate, phosphofructokinase converts fructose-6-phosphate to fructose-1,6-bisphosphate, and pyruvate kinase converts phosphoenolpyruvate to pyruvate. These irreversible steps ensure that once glucose enters glycolysis, it is committed to being broken down for energy production.
What molecule is the reactant in the first reaction of glycolysis?
http://wiki.answers.com/Q/What_molecule_is_the_reactant_in_the_first_reaction_of_glycolysis"
Which has a higher affinity for glucose: hexokinase or glucokinase?
Hexokinase
Which has a higher Vmax: glucokinase or hexokinase?
Glucokinase
What is a function of enzyme protein for example hexokinase?
Hexokinase is an enzyme involved in the phosphorylation of hexose (five carbon sugar). It speeds the process on adding a phosphorus to the sugar.
Which of these enzymes catalyzes the first reaction in glycolysis?
Hexokinase
How does ATP inhibit hexokinase?
ATP inhibits hexokinase by competing with glucose for binding at the active site of the enzyme. When ATP is bound, it causes a conformational change that prevents glucose from binding and being phosphorylated. This inhibition helps regulate the glycolytic pathway by ensuring that hexokinase is only active when ATP levels are low.
Which of the following is characteristic of hexokinase (as opposed to glucokinase)?
It is not inducible by insulin
Which of the following enzymes catalyzes an unfavorable step in glycolysis?
Hexokinase
What substrate is converted into glucose 6 phosphate by the enzyme hexokinase?
Glucose is the substrate that is converted into glucose 6-phosphate by the enzyme hexokinase. Hexokinase catalyzes the phosphorylation of glucose to glucose 6-phosphate in the first step of glycolysis.
Glucose to glucose 6-phosphate. Irreversible. Hexokinase/gluckokinase. Requires ATP and Mg2?
The conversion of glucose to glucose 6-phosphate catalyzed by hexokinase/glucokinase is an irreversible reaction that traps glucose within the cell. This process consumes one molecule of ATP and requires Mg2+ as a cofactor. Hexokinase has a high affinity for glucose and is present in most tissues, while glucokinase is found primarily in the liver and pancreas with a lower affinity for glucose.
Which enzyme in glycolysis is responsible for the conversion of glucose to glucose 6-phosphate?
Hexokinase
How does hexokinase maintain homeostasis?
Hexokinase helps maintain homeostasis by catalyzing the first step of glucose metabolism, converting glucose to glucose-6-phosphate, which traps glucose inside cells. This helps regulate blood glucose levels by controlling glucose uptake and utilization in cells. By initiating glycolysis, hexokinase also produces ATP, which is essential for energy production and cellular function.
What would happen if an organism lacked hexokinase?
If an organism lacked hexokinase, it would be unable to phosphorylate glucose to glucose-6-phosphate, which is the first step in glucose metabolism. This would impair the organism's ability to utilize glucose for energy production.
