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Barbara spent years of research and after a very careful study of many generation. In 1944 McClintock recognized Jumping of DNA, which refer to unstable of DNA to move around between the chromosomes. But for many years her theory was disregarded.

In 1983, the theory of jumping DNA or which is known today "Transposable" was confirmed. In 1983 McClintock was awarded The Nobel Prize in Genetics for the discovery of genetic transposition.

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What is a jumping gene or transposing?

Transposons are genes that move from one location to another on a chromosome. These stretches of DNA hop out of their original spot in the genome and then wedge themselves in another, random place. When they land, they may disrupt the activities of nearby genes.In a study published last year, jumping genes normally bind to TDP-43, a protein that has been linked to frontotemporal dementia and Lou Gehrig’s disease. So these jumping genes can be helpful, or they can be a problem depending on where they land.The research, published in Molecular Cell by a team from the University of Michigan Medical School and the Howard Hughes Medical Institute, answers a key question about how 'jumping genes' move to new DNA locations.The parasite in question isn’t a foreign beast, but rather a piece of DNA that carries its own instructions for making a piece of 'rogue' genetic material and two proteins that can help it jump. 'Jumping' allows this rogue copy to land anywhere in the DNA of a cell, causing a change called a mutation.


How is Barbara mcclintock famous?

Barbara mcclintock is famous for being the first person to study peculiar inheritance patterns found in the colors of Indian corn, jumping DNA refers to the idea that some stretches DNA are unstable and "transportable" i.e they can move around on and between chromosomes.


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