This is the genesis of new and fragile blood vessels following an occlusion (blockage) of an existing vessel. This phenomenon often occurs in the retina. It is widely considered to be highly undesirable as these fragile vessels are prone to hemorraging, thereby starving surrounding tissue of blood nutrients. Condition is traditionally treated by photocoagulation which is the use of lasers to cauterise these new vessels.
Neovascularization is different from angiogenesis by the way it appears. Capillary buds will grow out, or protrude, and will out grow their area when afflicted with angiogenesis.
Neovascularization in the eye is primarily caused by conditions that lead to hypoxia or insufficient oxygen supply to retinal tissues, such as diabetic retinopathy, age-related macular degeneration, and retinal vein occlusion. In response to low oxygen levels, the body releases vascular endothelial growth factor (VEGF), which stimulates the growth of new, often abnormal blood vessels. These new vessels can leak fluid and bleed, leading to vision impairment. Additionally, inflammation and other factors can contribute to the process of neovascularization.
Angiogenesis and neovascularization are two terms used to describe the formation of new blood capillaries in the body.
retinal breaks or detachments; retinal ischemia (retinal tissue that lacks oxygen); neovascularization (proliferation of blood vessels in the retina); Coats' disease
Neovascularization within the peritoneal layer refers to the formation of new blood vessels in the peritoneum, which is the tissue lining the abdominal cavity. This process often occurs in response to inflammation, injury, or conditions such as cancer, where increased blood supply is needed for tissue repair or tumor growth. Neovascularization can contribute to various pathological conditions, potentially leading to complications such as adhesions or peritoneal carcinomatosis. Understanding this process is important for developing therapeutic strategies in abdominal diseases.
Patients should be seen at least monthly for the first three months to monitor for signs of other complications, such as the abnormal formation of blood vessels (neovascularization) in the iris of the eye or glaucoma.
Untreated inclusion conjunctivitis in the newborn persists for 3-12 months and usually heals; however, there may be scarring or neovascularization. In the adult, if left untreated, the disease may continue for months and cause corneal.
Hemoglobin A1c, ketosis, hyperglycemia, hypoglycemia, somoyogi effect, nephropathy, retinopathy, neovascularization, end organ damage, microalbuminuria, peripheral neuropathy, C-peptide level, truncal obesity, basal dose, bolus dose, sliding scale, postprandial, hyperinsulinemia, insulin, ACE inhibitor.
Chondroradionecrosis (CRN) of the larynx is one of the most serious complications of radiation therapy. It may progress or become fatal despite aggressive treatment measures. Hyperbaric oxygen therapy (HBO) has been used to treat radiation necrosis of the head and neckHBO is thought to repair vascular beds within the irradiated tissue, enhancing neovascularization and wound healing. The efficacy of HBO in the treatment of laryngeal CRN has been described in only a few case reports and series.
The macula is a tiny spot in the center of the retina. There are several layers of tissue that bring nutrients and oxygen to the macula and remove built up waste products. One layer of tissue is called the choroid layer - this is a layer of blood vessels that helps with the transporting in nutrients and removing waste. In wet macular degeneration new but abnormal blood vessels grow and instead of helping with this transport system, they actually are harmful. The reason for this is that these abnormal blood vessels are very tiny and fragile - meaning that they leak fluid.Wet macular degeneration gets it's name because of this excess blood and fluid from leaky blood vessels.This abundance of fluid builds up under the macula and raises it which is what causes the distortion of vision - straight lines become wiggly or wavy.What causes these unusual blood vessels to develop? There is a term called angiogenesis which means "new blood vessels."Vascular endothelial growth factor (VEGF) is a protein secreted by cells that are oxygen deprived. VEGF stimulates the growth of these abnormal blood vessels.Healthy adults secrete very low levels of VEGF, while those who have health conditions such as cancer or age related macular degeneration secrete high levels of this protein.
Cosmetic Genecology - How it improves lives? The needs of women vary at different times in their lives, and we want to help them.” – Dr. Armen Kirakosyan (Aesthetic Gynecology Specialist) Introduction: The field of cosmetic gynecology is relatively new. The female vaginal anatomy can undergo unpleasant or unwanted alterations as a result of factors such as age, gravity, pregnancy, heredity, and chronic pelvic health conditions. Most women find these alterations distressing, but they go about their lives in silence because of changes in their pelvic supporting also a deeply personal issue that a few women bring up between themselves or even with their doctors. Why do Women Prefer It? According to research, alterations in the anatomy of the pelvis have a direct impact on sexual function. A woman’s physical health, well-being, contentment, self-esteem, and quality of life may be negatively impacted by illnesses such as pelvic organ prolapse, tissue stretching, and nerve damage, in addition to the changes that naturally occur after childbirth. Too many women assume they must live with an uncomfortable or unpleasant condition, ignorant that anatomical and functional alterations that naturally occur can be remedied. Restoring Vaginal Health – A Non-Surgical Non Invasive Strategy Surgical intervention may be necessary in some cases, but not in others. In any case, doctors always begin by discussing the least invasive options. A nonsurgical noninvasive treatment involves the process of using a laser for cosmetic gynecology. The application of laser in the genital area stimulates collagen production. Collagen fibre provides vaginal tissue its strength and pliability, much as they do in the skin. Diode laser technology has revolutionized vaginal tissue contraction and collagen production in Cosmetic Gynecology by gently heating vaginal tissue to a temperature that stimulates the development of new collagen. This enhances the functionality of the entire vaginal area by regulating blood flow, increasing lubrication, enhancing immunological resistance, and restoring the strength and suppleness of the vaginal walls How Does It help To Improve Women’s Aesthetics And Confidence? Through Laser Vaginal Rejuvenation (LVR) The vaginal mucosa loses tone as a result of aging and muscular tension in women, culminating in an atrophic process. Inflammation, dryness, and itching are all side effects of this condition, as well as tissue laxity, sexual dysfunction, and urine incontinence. Laser diode and laser handpiece action is combined in LVR process to speed up collagen formation and remodeling in the mucosa. Through Vaginal Tightening The laser procedure accelerates collagen regeneration and contraction of the elastin fibers, resulting in neovascularization and enhanced vaginal lubrication, by applying intense thermal heating and micro-ablation to the various vaginal layers. End result: thicker epithelium and new collagen fibers are embedded in the female genital tissue, resulting in a younger appearance and a smaller vaginal diameter. By Curing Stress Urinary Incontinence (SUI) One of the most prevalent and stressful conditions affecting a large number of females is Stress Urinary Incontinence (SUI). 30 percent of women between 30 and 60 years old have urine incontinence, with half of those (30 percent) being SUI, according to the American Urological Association. By Curing Vaginal Dryness & Recurrent Infections Lavatory concerns such as dryness and recurrent vaginal infections can be addressed by laser technology. Improved lubrication and normalization of the vaginal pH and flora can be achieved with the use of laser diode. The LVR treatment boosts the local immune system response and helps remove chronic vaginal infections. By Curing Post-Menopausal Genito-urinary Syndrome of Menopause (GSM) Menopause hormones cause the vaginal lining to shrink, dry up, lose its elasticity, and become irritated. The vaginal lining can be rejuvenated, the vaginal walls can be thickened, and natural lubrication can be restored with laser diode. As a result, unpleasant symptoms such as itching, burning, and friction are greatly reduced, resulting in improved sexual functioning and a better quality of life. Fore more Info: Mobile: +917306 700 964 #oreolacademy | #oreol | #oreolpromotions | oreolmedcare | #oreolmedline | #oreolmedtech
DefinitionMacular degeneration is an eye disorder that damages the center of the retina, which is called the macula. This makes it difficult to see fine details.Alternative NamesAge-related macular degeneration (ARMD); AMD; senile macular degeneration (SMD) is an older name that is no longer in common use.Causes, incidence, and risk factorsThe retina is the layer of tissue at the back of the inner eye. It changes light and images that enter the eye into nerve signals that are sent to the brain. The macula is the part of the retina that makes our vision sharper and more detailed.Macular degeneration is caused by damage to the area around blood vessels that supply the macula. This change in the blood vessels damages the macula.Two phases of macular degeneration (AMD) exist:Dry macular degeneration occurs when the blood vessels under the macula become thin and brittle. Small yellow deposits, called drusen, form under the macula. As these drusen increase in size and number, they create a blurred and dim spot in the central vision of the eye. Almost all people with macular degeneration start with the dry form.Wet macular degeneration occurs in only about 10% of people with macular degeneration. Brittle vessels break down and new abnormal and very fragile blood vessels grow under the macula. This is called choroidal neovascularization. These vessels leak blood and fluid, which leads to damage of the macula. Although only about 10 percent of people with macular degeneration have this form, it causes most of the vision loss associated with the condition.Scientists aren't sure what causes AMD. The disease is most common in people over 60, which is why it is often referred to as age-related macular degeneration.In addition to heredity, other risk factors are:Caucasian raceCigarette smokingHigh-fat dietFemale genderObesitySymptomsAt first you may not have symptoms. As the disease progresses, your central vision may be affected.The most common symptom in dry AMD is blurred vision. This is limited to the center of the field of vision. Often objects in the central vision look distorted and dim, and colors look faded. A patient may have trouble reading print or seeing other details, but can generally see well enough to walk and perform most routine activities.As the disease becomes worse, you may need more light to read or perform everyday tasks. The blurred spot in the center of vision gradually gets larger and darker. In the later stages, you may not be able to recognize faces until people are close to you.AMD typically does not affect side (peripheral) vision. This is very important, because it means you will never have complete vision loss from this disease.The most common early symptom of wet macular degeneration is that straight lines appear distorted and wavy. You may also notice a small dark spot in the center of your vision that gradually gets larger. Central vision loss can occur very quickly. If this occurs, you urgently need evaluation by an ophthalmologist with experience in retina disease.Signs and testsIf you are over age 60 and you've had changes in vision, your eye care provider will do an examination. During the exam, the doctor will use drops to enlarge (dilate) your pupils, and a special lens to view your retina and optic nerve.The doctor will look for changes in the blood vessels and the membrane that surrounds them. This may show drusen, the yellow deposits that form on this membrane in dry macular degeneration.You may be asked to cover one eye and look at a pattern of lines called an Amsler grid. If the straight lines appear wavy, it may be a sign of AMD.Other tests for macular degeneration may include:Fluorescein angiogramOptical Coherence Tomography (OCT)TreatmentNo treatment exists for dry macular degeneration. However, a combination of vitamins, antioxidants, and zinc may slow the progression of the disease. This combination of vitamins is often called the "AREDS" formula. Smokers should not use this treatment.The recommended supplements contain:500 milligrams of vitamin C400 international units of beta-carotene80 milligrams of zinc2 milligrams of copperAlthough there is no cure for wet AMD, treatments may include:Laser surgery (laser photocoagulation) -- a small beam of light destroys the abnormal blood vessels.Photodynamic therapy -- a light activates a drug that is injected into your body to destroy leaking blood vessels.Special medications that slow the formation of new blood vessels in the eye (anti-angiogenesis, anti-VEGF therapy) -- drugs such as bevacizumab (Avastin) and ranibizumab (Lucentis) are injected into the eye to stabilize or improve vision. This is a painless process.Low-vision aids (such as special lenses) and therapy can help you use the vision that you have more effectively, and improve your quality of life.Support GroupsAMD Alliance International -- (877) AMD-7171 -- www.amdalliance.org.Expectations (prognosis)Most people with mild dry macular degeneration will not have disabling central vision loss. However, there is no way to predict who will progress to a more severe form of the disease.The wet form of macular degeneration often leads to significant vision loss.Although macular degeneration can cause people to lose the ability to read, drive a car, and recognize faces that are not very close, it never causes complete blindness. This disorder results in the loss of central vision only -- macular degeneration cannot cause peripheral vision loss.Nearly everyone with macular degeneration can get around, eat, perform personal hygiene, and do other routine activities without too much difficulty.ComplicationsLoss of central vision may interfere with many daily activities, such as reading, working on the computer, or driving. You may need extra light or magnification to perform many of your normal activities.Calling your health care providerIf you have AMD, your health care provider may recommend that you check your vision every day on an Amsler grid. Call your provider immediately if the lines appear wavy, or you notice any other changes in your vision.PreventionAlthough there is no known way to prevent macular degeneration, lifestyle factors can reduce your risk of developing the condition:Don't smokeEat a healthy diet that is high in fruits and vegetables and low in animal fatExercise regularlyMaintain a healthy weightSee your eye care professional regularly for dilated eye exams.ReferencesAmerican Academy of Ophthalmology Preferred Practice Pattern in Macular Degeneration.The Age-Related Eye Disease Study (AREDS).Gohel PS, Mandava N, Olson JL, Durairaj VD. Age-related macular degeneration: an update on treatment. Am J Med. 2008;121(4):279-281.Martidis A, Tennant MTS. Age-related macular degeneration. In: Yanoff M, Duker JS, Augsburger JJ, et al., eds. Ophthalmology. 2nd ed. Philadelphia, Pa: Mosby Elsevier; 2004:chap 125.