The synaptic basis for learning and memory is long-term potentation (LTP), which is an increase in a synapse's firing potential after a brief, rapid stimulation.
An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.
A synaptic knob is a tiny bulge at the end of a terminal branch of a presynaptic neuron's axon!
synaptic/graded potential
K^+and Cl^-
What is the role of synaptic potentials in the perception of pain? What kind of reaction might you expect if synaptic potentials were removed?
A synaptic potential exists at the INPUT of a neuron (dendrite), and an action potential occurs at the OUTPUT of a neuron (axon). (from OldGuy)(from Ilantoren:) A synaptic potential is the result of many excitatory post synaptic potentials (epsp) each one caused by the synaptic vesicles released by the pre-synaptic terminus. If there are enough of these epsp then the responses will summate and depolarize the post-synaptic membrane at the axon hillock enough to fire an action potential.
IPSP - inhibitory post synaptic potential
The synaptic basis for learning and memory is long-term potentation (LTP), which is an increase in a synapse's firing potential after a brief, rapid stimulation.
An inhibitory postsynaptic potential (IPSP) is a kind of synaptic potential that makes a postsynaptic neuron less likely to generate an action potential.
This area is referred to as the synaptic cleft. This area is bound by the end of one neuron (the terminal bouton) and the post-synaptic membrane of the next neuron. When an action potential reaches the terminal bouton, Ca2+ influx triggers the release of neurotransmitters across the cleft, which bind to receptors on the post-synaptic membrane, allowing for an post-synaptic excitatory potential (PSEP) to be formed in the next neuron.
In general, action potentials that reach the synaptic knobs cause a neurotransmitter to be released into the synaptic cleft. The arrival of the action potential opens voltage-sensitive calcium channels in the presynaptic membrane.
A synaptic knob is a tiny bulge at the end of a terminal branch of a presynaptic neuron's axon!
synaptic/graded potential
Calcium ions enter the presynaptic neuron resulting in the release of neurotransmitter from the per-synaptic membrane. The neurotransmitter diffuses across the synaptic cleft, fusing with the receptors of the post-synaptic membrane. This changes the sodium channels to open and sodium ions will to flow into the post-synaptic neuron, depolarizing the post-synaptic membrane. This initiates an action potential. After the post-synaptic neuron has been affected, the neurotransmitter is removed by a type of enzyme called cholinesterase. The inactivated neurotransmitter then returns to the pre-synaptic neuron.
K^+and Cl^-
Potential, ok well we all know it's a potential, but which one? Is it Action Potential, Synaptic Potential or Membrane Potential. Just saying Potential isn't saying much?