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Addison's Disease is chronic failure of the adrenal glands which are located next to the kidneys. It can be treated with long term use of steroids, and with carefull and constant monitoring, the patient can live a fairly normal life span. Do a Google search for more info about this disease. There are a number of web sites that offer information about this. Jim B Toronto.

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Have people died from addisons disease?

Yes, if Addison's disease is not properly managed and treated, it can lead to life-threatening complications such as an adrenal crisis which can be fatal. However, with proper medication and management, individuals with Addison's disease can live a normal and healthy life.


How many people have Addison's Disease?

Addison's disease is estimated to affect 1 in 100,000 individuals globally. It is a rare condition caused by the dysfunction of the adrenal glands, leading to insufficient production of hormones like cortisol and aldosterone. Early diagnosis and proper management with hormone replacement therapy are crucial for individuals with Addison's disease.


Why is ACTH elevated in Addisons disease?

The steroid hormones produced by the adrenal cortex exhibit feedback inhibition on ACTH production, therefore a low concentration of corticosteroids (as seen in Addisons disease) will not exhibit this feedback inhibition. Without this inhibition, ACTH levels are not regulated and therefore rise.


What Hypofunctioning of the adrenal cortex leads to what condition?

Low adrenal functioning of the cortex leads to the cortex not making enough steroid hormones. It has two names: Primary AI or Addison (or Addison's) disease. In this rare condition, the adrenal glands do not work properly and cannot make enough cortisol (a "stress" hormone).


Is there a test for addisons disease?

Yes, there are several tests used to diagnose Addison's disease, including blood tests to measure cortisol and adrenocorticotropic hormone (ACTH) levels, and stimulation tests that evaluate the adrenal glands' ability to produce cortisol. Imaging tests may also be used to visualize the adrenal glands. Consulting with a healthcare provider is essential for accurate diagnosis and treatment.

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