Water. The carbon dioxide travels from the cell that produced it, through the interstitial fluid and the capillary wall, into a red blood cell. There it combines with water to make carbonic acid, which splits into a bicarbonate and a hydrogen ion. The hydrogen is picked up by the hemoglobin, and the bicarbonate diffuses into the plasma and is carried to the lungs. This acts as a buffer, accepting or releasing hydrogen ions to keep the blood pH at around 7.4. Once in the lungs, the bicarbonate reenters the red blood cell and combines with the hydrogen from the hemoglobin to produce carbonic acid. Then, it splits into water, which remains in the blood, and carbon dioxide, which is exhaled.
Carbonic anhydrase
Bicarbonate accpets H+ ions and forms carbonic acid.
describe how carbon dioxide is transported in the blood
Carbon dioxide is transported in our blood to the lungs in one of three ways: 1. Dissolved in the plasma (10% of CO2 does this) 2. Attached to one of the amino groups on hemoglobin, to form a carbaminohemoglobin (HbCO2) (about 30% travel this way) 3. As bicarbonate in the plasma (about 60% go this way) I think your question relates most to the last option, so I'll just cover that. For CO2 to move to the lungs as bicarbonate, a few things have to happen at the tissues: -The CO2 enters the red blood cell -The red blood cell has carbonic anhydrase, an enzyme in it -The carbonic anhydrase allows the CO2 to join with water, which forms Carbonic acid. That formula is: CO2+H2O (in the presence of carbonic anhydrase) → H2CO3 -Carbonic acid is a weak acid. It breaks apart in the red blood cell to H+ and HCO3- (a hydrogen ion and bicarbonate) -the HCO3- will trade places with an ion of Chloride, which is outside the Red Blood Cell, floating around in the plasma. The Cl- and HCO3- are both negatively charged, so no charge change takes place. This is called the chloride shift. -So now the bicarbonate is in the plasma, and the H+ is in the RBC. The H+ will join with a molecule of Hemoglobin to form HHb or HHbO2 if an oxygen is attached. -When the RBC reaches the lungs, the bicarbonate shifts again with the chloride ion, and it rejoins again with the H+ to form H2CO3 carbonic acid -Under normal circumstances, in a breathing human, this carbonic acid will split into H2O and CO2, and the CO2 will be exhaled. Your question however is about a child who is holding her breath. The transport of ions moves in the same way, but once in the lungs, the CO2 will not be able to be exhaled. So her blood CO2 levels will increase, which will cause her blood to become more acidic. She will be able to hold her breath consciously for a short time only; if she passes out, the chemoreceptors located in the medulla oblongata and the pons will detect a decrease in pH, and will increase breathing rate to restore homeostasis.
The molecule haemoglobin, which transports oxygen around the body (when it can be called oxy-hamoglobin) also transports the oxides of carbon, carbon dioxide (and, usually to a far lesser extent, carbon monoxide); when it is known as carboxy-haemoglobin.
20 bicarbonate : 1 carbonic acid
Sincerely, carbonic anhydrase enzyme. Followed by hemoglobin
Carbonic acid
Enzyme carbonic anhydrase forms carbonic acid (H2CO3) which dissociates into H+ and HCO3. 70% of carbon dioxide is transported in plasma as HCO3. BICARBONATE IONS.
bicarbonate and oxygen
They include: -Carbonic acid + bicarbonate -Acid/alkali Na salts of phosphoric acid -Plasma proteins + bases
The pKa value for sodium bicarbonate (NaHCO3) is 10.3. This provides a measure of the acid strength of bicarbonate. People often make the mistake of reporting the pKa value of 6.3 for bicarbonate. However, that is the pKa value of carbonic acid (not bicarbonate). It relates to the ease of the first deprotonation of carbonic acid to form bicarbonate. The pKa of bicarbonate relates to the deportation of bicarbonate to form carbonate. This distinction is important, since carbonic acid has two pKa's, the higher of which represents that second deprotonation.
sodium bicarbonate reacts with acetic acid to form sodium acetate and carbonic acid. carbonic acid will further dissociate to form water and carbon dioxide
magnesium bicarbonate
calcium bicarbonate is formed
H2CO3 is Carbonic Acid or HCO3- is Bicarbonate
yes