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What substance must be present in the stomach for pepsin to work best?
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∙ 11y ago
What substance must be present in the stomach for pepsin to work best? *
Mariane Griego
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How does pepsin work?
Pepsin is released by the Chief Cells in the stomach in response to the ingestion of food. It cleaves(breaks up) proteins into smaller groups of amino acids called peptides which can be further broken down by other enzymes later in the GI tract and then absorbed into the body. Specifically it cleaves the bond at the N-terminus of most aromatic amino acids.
What is needed to digest proteins?
Mainly, the enzyme Protease breaks up proteins into amino-acids. Also, proteins contain nitrogen which the body cannot use. Water is required to remove this nitrogen, bonding with if to form ammonia. This is subsequently secreted in urine.
Pepsin probably works best at a pH?
Pepsin was most active in acidic environment from 37 °C to 42 °C. The activity of pepsin was the highest in pH2.0, inactive above pH6.5, and completely denatured or irreversibly inactivated above pH8.0. Therefore, in the solution below pH8.0, pepsin can be reactivated after reacidification. The stability of pepsin at a high pH value is of great significance to the diseases caused by pharynx and larynx reflux. Learn more information at the Creative Enzymes website.
All enzymes act best at a pH close neutral?
This is not true. Different enzymes thrive in completely different pH conditions. Consider the protease pepsin, which works in the stomach. It breaks down proteins in acidities as low as pH 2. In the duodenum, lipase works best in slightly alkaline conditions.
What is the best carrier protein pump in animal cells?
Animal cells' best-known carrier pump is their stomach.
What type of enviorment does pepsin work best in?
The optimum pH of pepsin is pH2. Pepsin is found in the stomach and it is protease enzyme that digest protein into smaller molecule. The stomach is suitable place for it because it is acidic , so it's activity increases in the acidic environment.
Which enzyme works best in alkaline conditions?
Pepsin in the stomach
What susbance must be present in the stomach for pepsin to work best?
HCI or hydrochloric acid helps to lower down the Ph value of stomach and thus activates Pepsin, which is an enzyme present in most juices, and helps to break proteins into smaller peptides.
Pepsin a digestive enzyme found in the stomach works best at a pH near?
Pepsin works best in acidic environments and it's optimal pH (the pH at which it works best) is 2.0
Why does pepsin not remain active in the duodenum?
Yes. The precursor of pepsin is called pepsinogen; it is produced by stomach cells and then activated by the HCl in the stomach. Pepsin works best at very low pH.... e.g. acid conditions of the stomach. The small intestine has glands that produce neutralize the acid. Pepsin denatures at pH's of 5,0 or higher..... so effectively it is neutralized when the chyme enters the small intestine.
What happens to pepsin at pH of 8?
It denatures (enzyme breaks down) because pepsin is best operational in a pH of around 2 or 3 in the stomach juices.
Which enzyme works best in neutral conditions?
These are secreted by the stomach:pepsiogen precursor for pepsin (an enzyme)intrinsic factor (so that B12 can be absorbed)gastrin (a hormone)ghrelin (a hormone)Only pepsin fits your question as pepsiogen needs HCl to convert into pepsin.Pepsin.
In the stomach what is the acid called that breaks down the bolus?
The stomach consists of gastric gland that secrete gastric juices- HCl ,Renin and Pepsin. Pepsin acts upon proteins to convert them to peptides, smaller protein molecules. But, Hcl is needed for conversion of proteins as pepsin works best in aan acidic medium.
Which enzyme functions best in a pH environment most similar to that of human stomach enzyme?
Pepsin. It is located in the stomach. Pepsin helps with the breakdown of food and is a protein. A pH 2 is optimal for the human enzyme pepsin. If the pH level exceeds 7, pepsin becomes denatured or lose its structure; above pH 5,, it will increase function.
Where is Pepsin (protease) located in the body?
Pepsin is found in the stomach of a human being. It turns food proteins into peptides and is considered a digestive protease.
At what pH is the rate of enzyme activity the highest?
Pepsin secreted in the stomach, works at highly acidic pH and the pH could be as low as 2. The optimal pH for pepsin is thus near about 2. This pH is maintained by HCl secreted by the gastric glands in the stomach.
How would the digestion of food be affected if your stomach did not produce hydrochloric acid?
A person's inability to produce hydrochloric acid in the stomach is called achlorhydria. This condition affects the enzyme pepsin, which helps to break down proteins. Pepsin requires a low pH to be activated.
