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What substance must be present in the stomach for pepsin to work best? *

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Mariane Griego

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Why does pepsin, an enzyme found in the stomach, function best at an acidic pH?

Pepsin, an enzyme found in the stomach, functions best at an acidic pH because the acidic environment helps to activate and maintain its structure, allowing it to efficiently break down proteins into smaller molecules for digestion.


How does pepsin work?

Pepsin is released by the Chief Cells in the stomach in response to the ingestion of food. It cleaves(breaks up) proteins into smaller groups of amino acids called peptides which can be further broken down by other enzymes later in the GI tract and then absorbed into the body. Specifically it cleaves the bond at the N-terminus of most aromatic amino acids.


Which organ secrets enzymes that are active at a low pH?

The stomach secretes protease enzymes that work best at a pH of around 2.


Pepsin probably works best at a pH?

Pepsin was most active in acidic environment from 37 °C to 42 °C. The activity of pepsin was the highest in pH2.0, inactive above pH6.5, and completely denatured or irreversibly inactivated above pH8.0. Therefore, in the solution below pH8.0, pepsin can be reactivated after reacidification. The stability of pepsin at a high pH value is of great significance to the diseases caused by pharynx and larynx reflux. Learn more information at the Creative Enzymes website.


How does pepsin break down proteins in the digestive system?

Pepsin breaks down proteins in the digestive system by breaking the bonds between amino acids, which are the building blocks of proteins. This process is called hydrolysis, where water molecules are used to split the protein molecules into smaller fragments that can be easily absorbed by the body. Pepsin works best in the acidic environment of the stomach, where it is activated from its inactive form, pepsinogen, and can start breaking down proteins into peptides.

Related Questions

What type of enviorment does pepsin work best in?

The optimum pH of pepsin is pH2. Pepsin is found in the stomach and it is protease enzyme that digest protein into smaller molecule. The stomach is suitable place for it because it is acidic , so it's activity increases in the acidic environment.


Which enzyme works best in alkaline conditions?

Pepsin in the stomach


What susbance must be present in the stomach for pepsin to work best?

HCI or hydrochloric acid helps to lower down the Ph value of stomach and thus activates Pepsin, which is an enzyme present in most juices, and helps to break proteins into smaller peptides.


Why does pepsin not remain active in the duodenum?

Yes. The precursor of pepsin is called pepsinogen; it is produced by stomach cells and then activated by the HCl in the stomach. Pepsin works best at very low pH.... e.g. acid conditions of the stomach. The small intestine has glands that produce neutralize the acid. Pepsin denatures at pH's of 5,0 or higher..... so effectively it is neutralized when the chyme enters the small intestine.


Why does the digestive enzyme pepsin need to enjoy acidity?

Pepsin is an enzyme in the stomach that works best in an acidic environment because it is activated by the low pH. The acidity helps to unfold the protein molecules in food, making them more accessible to pepsin for breaking down into smaller peptide chains. This acidic environment also helps to kill harmful bacteria that may be present in the food.


Pepsin a digestive enzyme found in the stomach works best at a pH near?

Pepsin works best in acidic environments and it's optimal pH (the pH at which it works best) is 2.0


Does pepsin work best in an alkaline environment?

No, pepsin works best in an acidic environment. It is an enzyme produced in the stomach, where the pH is around 1.5-2, which is highly acidic. In this acidic environment, pepsin can efficiently break down proteins into peptides.


Where in the digestion system do pepsin and hydrochloric acid begin the splitting of the proteins?

Pepsin and hydrochloric acid begin the splitting of proteins in the stomach. Pepsin is an enzyme produced in the stomach that works best in acidic conditions, which is created by hydrochloric acid secreted by the stomach lining. Together, they help break down proteins into peptides for easier absorption in the small intestine.


Which enzyme works best in neutral conditions?

These are secreted by the stomach:pepsiogen precursor for pepsin (an enzyme)intrinsic factor (so that B12 can be absorbed)gastrin (a hormone)ghrelin (a hormone)Only pepsin fits your question as pepsiogen needs HCl to convert into pepsin.Pepsin.


Why does pepsin, an enzyme found in the stomach, function best at an acidic pH?

Pepsin, an enzyme found in the stomach, functions best at an acidic pH because the acidic environment helps to activate and maintain its structure, allowing it to efficiently break down proteins into smaller molecules for digestion.


In the stomach what is the acid called that breaks down the bolus?

The stomach consists of gastric gland that secrete gastric juices- HCl ,Renin and Pepsin. Pepsin acts upon proteins to convert them to peptides, smaller protein molecules. But, Hcl is needed for conversion of proteins as pepsin works best in aan acidic medium.


Which enzyme functions best in a pH environment most similar to that of human stomach enzyme?

Pepsin. It is located in the stomach. Pepsin helps with the breakdown of food and is a protein. A pH 2 is optimal for the human enzyme pepsin. If the pH level exceeds 7, pepsin becomes denatured or lose its structure; above pH 5,, it will increase function.