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What triggers a inflammatory response?

Updated: 8/10/2023
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βˆ™ 12y ago

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The inflammatory response (inflammation) occurs when tissues are injured. Leukocytes and plasma proteins gather to inflame the area to fight infection. is a nonspecific defense reaction to tissue damage caused by injury or infection

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βˆ™ 7y ago
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βˆ™ 13y ago

Nonspecific resistance is the body's defense against pathogens. Defenses include external barriers like the skin and mucous membranes. If the pathogen breaks through those, a second line of defense includes leukocytes, macrophages, antimicrobial proteins, immune surveillance, inflammation, and fever.

Nonspecific defense differs from specific defense in that nonspecific defense doesn't rely on prior exposure. These defenses are natural in our body to protect.

Specific defenses are created from prior exposure to a pathogen and will only protect against that particular pathogen.

Saladin, Kenneth S. "Anatomy & Physiology: The Unity of Form and Function, Fifth Edition." McGraw Hill Higher Education, 2010.

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βˆ™ 13y ago

A minor infection, cause by a cut on the skin which causes bacteria to come through.

This is kind of hard to explain as it's more of a series of processes that occur in succession, but here it goes :)

Chemical alarm due to a flood of inflammitory chemicals is released into the extracellular fluid. These chemicals include but are not limited to histamine, complement, kinins and prostoglandins. These chemicals contribute to such activities as vasodilation ( increased diameter of blood vessels) which leads to hyperemia (commonly seen as the redness around a cut also causes heat), this locally increased temperature increases the metabolic rate of cells (speeds up the healing process) the release of leukocytosis inducing factor (leukocytosis then occurs) and increased capillary permeability which causes protein rich fluid to be leak into interstitial tissue space causes pain and swelling limiting the movement of the affected area . This process also leaks clotting proteins to form interstitial clots that will help protect injury to surrounding tissue. Bear surface membrane receptors called Toll-Like receptors (TLRs, 11 types have been identified so far ) trigger the release of chemicals called cytokines that promote inflamation and attract WBCs (white blood cells) this process is called chemotaxis. which leads to the migration of leukocytes to the injured area, margination (clinging of leukocytes to cell walls, diapedesis (passing of WBCs through capillary walls), phagocytosis of pathogens and dead tissue cells. A temporary fibrin patch is formed. Healing begins.

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βˆ™ 9y ago

Carbohydrates with a high glycemic index (i.e.: Junk food, candy, refined sugar and more) are what triggers a powerful inflammatory response in humans. If you are allergic to dairy and wheat this will also trigger an inflammatory response.

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βˆ™ 14y ago

mast cells release histamine, serotonin and heparin

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βˆ™ 14y ago

The inflammatory response system is triggered when Mast cells release histamines and heparin.

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βˆ™ 11y ago

in the inflammatory responce ,fluid andwhhite blood cells leak from blood vessels into nearby tissues.

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βˆ™ 12y ago

Omega six fatty acids

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