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PTU reduces the amount of T3 thyroid hormone in the blood by reducing its secretion from the thyroid and by decreasing the peripheral conversion of T4 to T3.

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Q: What was the effect of propylthiouracil?
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What is propylthiouracil used for?

Propylthiouracil is used to treat hyperthyroidism. It works by stopping the thyroid gland from making thyroid hormone. Propylthiouracil should usually be given only to people who are allergic to or cannot tolerate methimazole (Tapazole) or who are in the first trimester of a pregnancy.


Why does propylthiouracil change the metabolic rate seen in a thyroidectomized rat?

Propylthiouracil is an additive that reversibly abolishes thyroid function and the thyroid controls how quickly the body burns energy.


The drug propylthiouracil is used to treat hypothyroidism or hyperthyroidism?

Propylthiouracil (PPU) is used to treat hyperthyroidism.


Can you drink alcohol while taking Propylthiouracil?

Propylthiouracil is a drug that may be prescribed by a doctor for the treatment of an overactive thyroid gland. No, you should not drink alcohol while taking this medication because it may cause sedation or confusion.


What natrally occurring porblems does propylthiouracil mimic?

Abnormal liver blood test and liver problems.


Is propylthiouracil used for hypothyroidism or hyperthyroidism?

Propylthioracil (PTU) is used in the treatment of some hypERthyroid conditions.


If propylthiouracil was injected what change in metabolic rate would you see in a thyroidectomized rat?

The weight in grams of the Thyroidectomized rat seemed to decrease when injected with propylthiouracil. Injected with tyroxine caused an increase in grams and ml of O2 levels do to the fact that tyroxine (a hormone from tyroid gland) increase the basal metabolic rate. ATT; Veronica V.


Why is methimazole used in treating thyrotoxic myopathy?

Propylthiouracil and methimazole are medications that inhibit production and release of thyroxine and also block tissue effects of thyroxine


What is the effects of tsh injection on normal rat?

Propylthiouracil is a drug given to patients with goiter to decrease or slow down basal metabolic rate.


Why would TSH have no effect on the metbolic rate of the thyroidectomized rat?

The only effect of TSH (Thyroid Stimulating Hormone) is to stimulate the thyroid gland tissue to produce thyroxine. If there is no longer a thyroid gland to stimulate, the TSH is produced in great abundance, but with no effect.


What medication is administered to slow the ability of the thyroid gland to produce thyroid hormone?

Antithyroid medications are used to slow down the thyroid gland's ability to produce thyroid hormones. The most common antithyroid medications are propylthiouracil (PTU) and methimazole (Tapazole). These medications are most commonly prescribed to patients diagnosed with hyperthyriodism or Graves' disease.


If propylthiouracil was injected what change in metabolic rate would you see in a hypophysectomized rat?

Purely guessing here, I'd assume a slowdown in overall metabolic rate. You've excised the pituitary gland, and adminsitered a thryoid antagonist. Unless there's some weird sympathetic reaction, a slowdown seems emminent.