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The Output (ml/min) of the Left Ventricle increases proportionally (approx.) to the Filling Pressure (that is, the pressure with which the blood returns to the heart), measured with respect to Intrathoracic Pressure. An increase in the latter will then produce a decrease in Cardiac Output, so the rate of blood returning to the heart decreases.

That is in the short term. But just after the increase in intrathoracic pressure, the Baroreceptors in the thorax sense the drop in pressure difference and trigger a reflex to increase Heart Rate, in order to restore blood flow. So if the lifting is prolongated, the rate of blood returning to the heart finally comes back to normal level.

The opposite reaction is produced when you inhale deeply and hold your breath.

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Q: When a person strains to lift a heavy object intrathoracic pressure increases What do you think will happen to the rate of venous blood returning to the heart during such lifting?
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