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Its not exactly that there's a material that thickens and becomes chromosomes as much as that the Chromatin (DNA) gets wrapped around certain proteins (Histones), which condenses it, and makes it visible in the form of Chromosomes (long strands of DNA that have been wrapped tight enough around proteins that they are visible),

So the answer you're looking for is either chromatin or DNA (i think that's what you meant by your question)

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Q: When the cell is preparing to divide the material that thickens and becomes the chromosomes is what material?
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