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Where is substantia nigra located?

Updated: 4/28/2022
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13y ago

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The substantia nigra are located in an area of the brain around the lateral ventricles known as the basal ganglia.

This is an addition to the above-mentioned answer. To be more specific, substantia nigra lies in the midbrain, dorsal to the cerebral peduncles.

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Q: Where is substantia nigra located?
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Post-encephalitic syndrome is a disease believed to be caused by a viral illness, that triggers degeneration of the nerve cells in the substantia nigra. Overall, this degeneration leads to clinical Parkinsonism and the disease is followed by encephalitis lethargica, a condition also referred as Von Economo's encephalitis.


What does the midbrain control?

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Which system controls voluntary behavior?

The somatic nervous system delivers the impulse to the skeletal muscles to produce mobility and locomotion to the body. This is what we regard as voluntary behavior. The impulse is generated in the frontal lobes of the cerebrum of the brain. This is also referred to as the motor cortex and is part of the central nervous system. It sends its impulse to the peripheral nervous system which is divided into the autonomic (involuntary) nervous system and the somatic nervous system (voluntary) and it carries out the instructions on how to move to create behavior. The primary motor cortex of the frontal lobe is primarily involved in somatic motor control, however also of great importance are deeper brain structures of the basal ganglia and the cerebellum or hind brain. These areas are involved in the initiation and coordination of muscle movements as well as muscle tone. For example, damage to the cerebellum suffered at birth has been associated with muscle spasticity, while deterioration of the basal ganglia structures - in particular the substantia nigra of the mid brain, is implemented in the disease pathology and cause of some of the symptoms of Parkinson's disease.


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Related questions

What happens when the substantia nigra is damaged?

Degeneration of neurons especially in substantia nigra of both sides might cause Parkinson's disease.


What is dopamine secreted by?

substantia nigra


The brain structure that produces dopamine?

substantia nigra


What does Eldepryl do?

It may slow degeneration of the substantia nigra


What is substantia nigra also known as?

black substance


What is black substance also known as?

substantia nigra


What is the Substantia nigra?

One of the movement control centers of the brain


What is the relation between substantia nigra and alzheimer's disease?

The substantia nigra is best known for its production of dopamine, a major neurotransimitter used in certain cell populations in the brain. The most common link with respects to pathology, is in Parkinson's disease, where these cell populations (in the substantia nigra) die off, and the brain has very low amounts of dopamine to work with. Sorry I couldn't be more specific to the alzheimer's respects, but I'm just giving what I know. Take care.


What disease results from a degeneration of dopamine-released neurons of the substantia nigra?

these two structures take part in complex control loops that govern certain aspects of movement and, when substantia nigra cells degenerate, these loops are disrupted and movements become unregulated, producing the symptoms of Parkinson's disease.


Does Parkinson's disease affect the brain stem?

No, parkinson's affects the dopaminergic neurons of the substantia nigra, which is part of the mid-brain.


Where is dopamine located?

Dopamine is produced in the substantia nigra of the brain as well as in the ventral tegmental area (VTA) of the midbrain and the arcuate nucleus of the hypothalamus.


What has the author P H M F van Domburg written?

P. H. M. F. van Domburg has written: 'The human substantia nigra and ventral tegmental area' -- subject(s): Aging, Anatomy & histology, Basal Ganglia Diseases, Mesencephalic tegmentum, Pathology, Substantia Nigra, Tegmentum Mesencepahli