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  • Parasympathetic innervation to the salivary glands is carried via cranial nerves. The parotid gland receives its parasympathetic input from the glossopharyngeal nerve (CN IX) via the otic ganglion, while the submandibular and sublingual glands receive their parasympathetic input from the facial nerve (CN VII) via the submandibular ganglion. These nerves release acetylcholine and substance P, which activate the IP3 and DAG pathways respectively.
  • Direct sympathetic innervation of the salivary glands takes place via preganglionic nerves in the thoracic segments T1-T3 which synapse in the superior cervical ganglion with postganglionic neurons that release norepinephrine, which is then received by β-adrenergic receptors on the acinar and ductal cells of the salivary glands, leading to an increase in cyclic adenosine monophosphate (cAMP) levels and the corresponding increase of saliva secretion. Note that in this regard both parasympathetic and sympathetic stimuli result in an increase in salivary gland secretions.[3] The sympathetic nervous system also affects salivary gland secretions indirectly by innervating the blood vessels that supply the glands.
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13y ago
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14y ago

Cranial Nerves VII (Facial) and IX (Glossopharyngeal)

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facial nerve (VII cranial nerve)

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Fascial

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hypoglossal

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Q: Which cranial nerves innervate salivary glands?
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Related questions

Which nerves innervate the taste buds?

Brances of the Facial (VII), Glossopharyngeal (IX), and Vagus (X) cranial nerves carry information about taste


Which cranial nerve is involved in the secretion of saliva?

CN VII (facial) The cranial nerves that regulate salivation are CN VII (facial) and CN IX (Glossopharyngeal). The cranial nerves that transmit the special sense of taste are CN VII (facial, to the anterior 2/3rd of the tongue) and CN X (vagus, to the posterior 1/3rd of the tongue). Of these nerves, only CN VII (facial) transmits both taste and salivation control.


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Because somebody would ask why it wasn't cranial nerves instead of brainial nerves.


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