Why can't big molecules pass through cell wall?

Answer 1

The phospholipid bilayer is semipermeable, meaning in cases other than bulk transport-endocytosis&exocytosis-, it does not compromise its own integrity to allow molecules to enter. The molecules that can most easily diffuse through a cell membrane are small, nonpolar molecules such as N2, O2, and CO2. Ions and polar molecules will have a difficult time crossing the membrane even if they are small because of the middle, hydrophobic layer. They can still pass through, just not as easily. Large molecules, however, cannot pass through the membrane due to their size, regardless or their polarization, and so they rely on those proteins embedded in the bilayer to transport them across (or, in some cases, endocytosis, which is when the cell membrane forms a kind of pocket - looks like a little mouth- and just engulfs the molecules). In this way the proteins are the only gap in what you could imagine as a sort of very fine and very picky filter. Larger molecules cannot get through the mesh of the filter and so they need to be recognized and passed through by those helpful little proteins.

Answer 2

Big molecules cannot pass through the cell wall because the cell wall is a rigid structure made of cellulose or other materials that restrict the movement of large molecules. This selective barrier helps protect the cell from harmful substances and maintain its internal environment. Instead, large molecules are typically transported into and out of the cell through specific transport proteins or processes.

Answer 3

Because they are large. Hard to diffuse and toxic potential

Answer 4

Cell membranes arepartially permeable. They do not allow laarge molecules to pass

Answer 5

because it is to big