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If we take duplet code for four bases then would be 16 codon which are not enough for 20 amino acids If the code is triplet it will give 64 codons their will be excess of 44 codon and therefore more then one codons are present for same amino acid. The excess will be still greater if more then three letter words are used. In the quardruplet code there will be 256 possibilities which is not possible. It was proved by NIRENBERG, KHORANA & HOLLEY(1968), they used in vitro system for the synthesis of a polypeptide using an artificial mRNA molecule.

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Q: Why the sequence of codons should be triplet but not doublet or quadraplet?
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The order of bases in a molecule of mRNA is determined by the sequence?

The base sequence of mRnas is 'determined by the base sequence of nucleotides in Dna.' The base sequence is transformed into information via the triplet codons of The Genetic Code.


A codon is a triplet base sequence?

mRNA


What are the complement of the codons and are found on the opposite side of he rna?

tRNA (or transfer RNA) molecules contain an anti-codon loop that contains within it a triplet complementary nucleotide sequence to that of the codon. This triplet is called the anti-codon


The triplet code means that 64 codons translate into only 20 amino acids. What are the additional 44 codons used for?

The triplet code means that 64 codons translate into only 20 amino acids. The additional 44 codons are not used for anything, but they are rather a redundancy in the code.


How is identity obtained from Dna?

The exquisitely Short Answer is "The Triplet code that is the result of the USE of the TRIPLET CODONS is how Identity is Obtained via Dna."


How are codons used in polypeptide formation?

Four 'types' of nucleotide bases - when they are read three-at-a-time - this is considered to be a triplet-codon. Triplet codons are individually related to one specific amino acid, a polypeptide being a short protein.


What is the relationship between the linear sequence of codons on mRNA and the linear sequence of amino acids in a polypeptide?

The linear sequence of codons on mRNA determines the linear sequence of amino acids in a polypeptide.


What is the difference between codon and anticodon?

A codon is the triplet sequence in the messenger RNA (mRNA) transcript which specifies a corresponding amino acid (or a start or stop command). An anticodon is the corresponding triplet sequence on the transfer RNA (tRNA) which brings in the specific amino acid to the ribosome during translation. The anticodon is complementary to the codon, that is, if the codon is AUU, then the anticodon is UAA. There are no T (Thymine) nitrogen bases in mRNA. It's replaced by U (Uracil).


What is the importance of the codons in protein synthesis?

A codon is the triplet sequence in the messenger RNA (mRNA) transcript which specifies a corresponding amino acid (or a start or stop command). An anticodon is the corresponding triplet sequence on the transfer RNA (tRNA) which brings in the specifieds amino acid to the ribosome during translation. The anticodon is complementary to the codon, that is, if the codon is AUU, then the anticodon is UAA. No Thymine's in mRNA. It's replaced by Uranine


Where are serine and alanine located in the protein chain?

Wherever their associated triplet codons occur within the associated mRna's.


What is directly responsible for the sequence of amino acids in a protein?

The sequence of codons in mRNA, or messenger RNA, is most directly responsible for the sequence of amino acids in a protein. Each codon is comprised of 3 nucleotides.


What codon sequence does DNA use?

There are 64 different codons. Refer to the related link for a table of DNA codons.