by injecting the sample in to a HPLC system having PDA detector or Scan the Quetiapine Fumarate sample solution in UV range.
intrinsic property
495
251 NM
The same as for any particle absorbing electromagnetic radiation: the wavelength at which the largest amount of absorption occurs.
Because in homo-annular ring distance between C1 and C4(of butadiene structure in it) is less compare to C1 and C4 of heteroannular.So, in Homo-annular more overlap of pi system, more conjugation, more lamda max.
The lambda max is 510 nm.
The reported UV lambda max of Vildagliptin drug is 254 nm.
257 nm
intrinsic property
495
251 NM
236nm
520 nm
uv max of pregabalin are following: 1.in water 276nm 2.in methanol 210nm
254 nm
The base value of this structure is 253 nm. There are 4 alkyl substituents which add a value of 20 (4x5 nm). So the lambda max of this structure is 273 nm.
using uv-visible spectrophotometer concentration vs absorbance is plotted and the maximum absorbance of the drug is lambda max of the drug. then after it will decrease. still if needed clarification, refer beer lambert"s law