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Use the smallest volume graduated cylinder capable of holding the liquid to measure, this will result in the most accurate result.

First, to insure greatest accuracy, one should make sure conditions are appropriate for the use of the cylinder, meaning that most graduated cylinders are calibrated for use with water at 20 degrees Celsius. One can determine this by looking for "20° TC" or "20° TD" marked on the cylinder. "TC", or "to contain", means that the volume of liquid contained in the cylinder is what is indicated by the graduated markings. "TD", or "to deliver", means the volume of liquid indicated by the markings is what will be delivered when the liquid is dispensed. This difference exists because when liquid is dispensed from any glassware a small amount remains and "TD" takes this difference into account.

Second, the liquid should be poured into the cylinder carefully down one side, tilting the cylinder to minimize splashing and the formation of bubbles.

Finally, to read the liquid volume, the cylinder should be on a level surface and the liquid level read at the bottom of the meniscus at eye level.

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