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Well, it depends on what it is. Is it a prescription medication? If it is something like amoxicillin (Amoxil), azithromycin (Zithromax), cefdinir (Omnicef), etc. then yes. Those are suspensions so you always want to shake those well before each use.

There is no need to shake a gel because it doesn't settle.

Generally, colloids shouldn't need to be shaken. Milk is an example of a colloid.

Solutions can be shaken every once in a while but it won't hurt if you don't shake them.

-Syrich

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Q: If the label on a medicine bottle said shake well before using the medicine is a solution a suspension a colloid or a gel?
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