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That would have to be a shared honor. The group on the far right side of the Periodic Table are known as the Noble Gases, because they don't "mix" with the other elements. This is because their outer electron shells are full so they don't form bonds.

However, one of the Nobles, Xenon, can, under some pretty rigorous laboratory conditions, be made to compound with Fluorine, with is the most active element, so perhaps it's only "semi-noble."

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