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Millon's test is given by any compound containing a phenolic hydroxy group. Consequently, any protein containing tyrosine will give a positive test of a pink to dark-red color. The Million reagent is a solution of mercuric and mercurous ions in nitric and nitrous acids (CAUTION: MILLON'S REAGENT IS HIGHLY TOXIC AND HIGHLY CORROSIVE). The red color is probably due to a Mercury salt of nitrated tyrosine.

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