What is the difference between endopeptidase and ectopeptidase?

Answer 1

Endopeptidase targets peptide links between amino acids in the middle of the protein chain whereas exopeptidases (or ectopeptidases) target the available "ends" of the amino acid chain. This is explains why in the Human body proteins are subject to endopeptidase action before exopeptidase to ensure the maximum amount of "ends" (larger surface area) is possible, increasing efficiency.

Answer 2

Endopeptidases cleave peptide bonds within a polypeptide chain, while ectopeptidases cleave peptide bonds at the ends of a polypeptide chain. Endopeptidases break down proteins into smaller peptides, while ectopeptidases trim off amino acids from the termini of proteins.