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How does the acid form in the stomach?
The acid in the stomach is produced by specialized cells called parietal cells. These cells secrete hydrochloric acid as well as intrinsic factor, which helps in the absorption of vitamin B12. The stomach lining also has a protective layer of mucous to prevent damage from the acid.
What makes up gastric fluid?
Gastric fluid is composed primarily of hydrochloric acid, along with enzymes like pepsin for protein digestion, mucus for protection of the stomach lining, and intrinsic factor for vitamin B12 absorption. It also contains electrolytes such as sodium, potassium, and chloride.
When the pH in a stomach increases from 2 to 4 How does the hydrogen ion concentration change?
When the pH in a stomach increases from 2 to 4, the hydrogen ion concentration decreases by a factor of 100. This is because the pH scale is logarithmic, with each unit change representing a tenfold difference in hydrogen ion concentration.
What causes pro-time levels to be too low?
Low prothrombin time (pro-time) levels can be caused by conditions such as liver disease, vitamin K deficiency, or use of certain medications like anticoagulants. It can also be due to clotting factor deficiencies or abnormalities in the intrinsic or extrinsic clotting pathways.
Why 6th coagulation factor is not mentioned about?
Factor VI is not generally included in discussions about coagulation factors because it was previously thought to be an activated form of factor V. Further research has since shown that factor VI is not a distinct factor.
Which cells produce intrinsic factor?
Intrinsic factor is produced in the fundus and body of the stomach by parietal cells that line the stomach. The purpose of intrinsic factor is so vitamin B can be absorbed in the small intestine.
How stomach helps in erythropoiesis?
parietal cells which can be found in gastric gland of stomach secretes intrinsic factor, which is a type of glycoprotein. this intrinsic factor, together with vitamin B12 is required for effective absorption of iron in small intestine. iron is required in erythropoiesis to produce haemoglobin. if iron absorption is low, RBC production will be affected. in summary, stomach helps in RBC production by producing intrinsic cells required in iron absorption.
What the importance of intrinsic factor?
Intrinsic factor is glycoprotein that is produced by the parietal cells of the stomach.
Why do you need intrinsic factor?
Intrinsic factor or gastric intrinsic factor is a protein produced by the stomach. It is used to absorb vitamin B12 in the small intestine. When there is a deficiency of the Intrinsic factor, there is a deficiency in the absorption of B12 into the body and this leads to pernicious anemia.
Aids in absorption of vitamin b12?
Intrinsic factor, a protein produced in the stomach, helps in the absorption of vitamin B12. This vitamin is crucial for red blood cell formation and neurological function. Absorption of vitamin B12 occurs in the small intestine, where it binds to intrinsic factor for transport into the bloodstream.
Which nutrient requires intrinsic factor for absorption?
Vitamin B12 requires intrinsic factor for absorption in the small intestine. Intrinsic factor is produced by the stomach and binds to vitamin B12 to facilitate its absorption in the ileum. Without intrinsic factor, vitamin B12 absorption is impaired, leading to deficiency.
What enables absorption of b12 across small intestine wall?
Intrinsic factor, a protein produced by the stomach, is required for the absorption of vitamin B12 in the small intestine. In the small intestine, vitamin B12 binds to intrinsic factor, forming a complex that can be absorbed through the intestinal wall.
A protein secreted by the stomach that is necessary for the absorption of vitamin B12?
The protein secreted by the stomach that is necessary for the absorption of vitamin B12 is called intrinsic factor. Intrinsic factor binds to vitamin B12 in the small intestine, allowing for its absorption into the bloodstream. Without intrinsic factor, vitamin B12 cannot be effectively absorbed and can lead to a deficiency.
Which vitamin need instritic factor for stomach for absortion?
B12 is the vitamin that requires intrinsic factor for absorption. B12 is also known as cobalamin.
Inadequate intrinsic factor is associated with?
Inadequate intrinsic factor is associated with vitamin B12 deficiency, as intrinsic factor is necessary for the absorption of this essential nutrient in the gut. Vitamin B12 deficiency can lead to symptoms such as anemia, fatigue, and neurological problems. It is commonly seen in individuals with pernicious anemia or autoimmune conditions affecting the stomach lining.
The most important function of the stomach and perhaps the only function that appears to be essential for life is the?
secretion of intrinsic factor
Where does the absorption of vitamin B12 occur?
The vitamin B12 is a very important nutrient; it lowers risk of stroke, heart disease, cancer, Parkinson's, and Alzheimer's disease. The vitamin begins to absorb in the mouth, in contrast to most nutrients.
