Ciba & lepetit pharmaceuticals. They got the prestigious prix galien award for excellence in scientific innovations.
Aluminum was first discovered in Denmark.
The first gas to be discovered was hydrogen. It was discovered by chemist Henry Cavendish in 1766.
Nitrogen was discovered in northern Scotland!
Celluloid was discovered by John Wesley Hyatt in 1869 as a substitute for ivory in billiard balls.
I was discovered in a lab, not found in nature.
Rifampicin is an antibiotic that inhibits bacterial RNA polymerase, preventing transcription of essential genes. When used in selection of Agrobacterium, it targets and kills non-transformed cells that do not contain the resistance gene, allowing only transformed cells to survive due to their ability to withstand rifampicin.
Risorine kit contains the standard formulation of anti tubercular drugs with the difference that the dose of rifampicin is reduced from 450 mg to 200 mg,a decrease of about 60 %.Since rifampicin is put in a lesser dose,therefore the side effects are also correspondingly much less.However since the rifampicin is boosted,the dose of 200 mg boosted rifampicin works better than that when given in 450 mg.
Yes
Rifampicin primarily targets bacterial RNA polymerase, inhibiting transcription and thus preventing the synthesis of essential proteins in Gram-negative bacteria like Escherichia coli. By disrupting RNA synthesis, rifampicin effectively stifles bacterial growth and replication. However, its efficacy can be limited due to the inherent permeability barriers of the Gram-negative cell envelope and the potential for developing resistance. Consequently, while rifampicin can be effective against E. coli, it is often used in combination with other antibiotics for enhanced effectiveness.
Red urine in patients taking rifampicin is primarily due to the drug's ability to cause discoloration of bodily fluids. Rifampicin is a potent antibiotic that can impart a reddish-orange hue to urine, sweat, and tears due to its chemical structure. This discoloration is harmless and is a common side effect of the medication, resulting from the excretion of the drug and its metabolites. It is important for patients to be informed about this side effect to avoid unnecessary concern.
Rifampicin has a half-life of approximately 3 to 5 hours in healthy individuals, meaning it takes this amount of time for half the drug to be eliminated from the body. Generally, it can take about 1 to 2 days for rifampicin to be cleared from the system after the last dose, depending on factors like metabolism, dosage, and duration of use. However, traces of the drug may be detectable in urine for a longer period. Always consult a healthcare professional for personalized information.
multiple drugs need to be used, usually for 6 months. Might include rifampicin, isoniazid, pyrazinamide, ethambutol
The duration of rifampicin treatment typically depends on the condition being treated. For tuberculosis, it is usually taken for at least 6 months as part of a combination therapy. In cases of other infections, such as certain staphylococcal infections, the duration may vary from a few weeks to several months. Always follow a healthcare provider's guidance regarding the specific treatment regimen.
Two antibiotics that affect nucleic acids in bacteria are ciprofloxacin and rifampicin. Ciprofloxacin inhibits DNA gyrase, an enzyme crucial for bacterial DNA replication, while rifampicin targets RNA polymerase, disrupting RNA synthesis. Both antibiotics are effective against a variety of bacterial infections by interfering with essential nucleic acid processes.
Some of the drug is excreted in bodily fluids which tints it red. It's not a bad sign.
Leprosy, caused by the bacterium Mycobacterium leprae, is primarily treated with a combination of antibiotics known as multidrug therapy (MDT). The standard regimen includes rifampicin, dapsone, and clofazimine. Rifampicin is effective in killing the bacteria, while dapsone and clofazimine help prevent resistance and manage the disease. Treatment typically lasts for six months to a year, depending on the severity of the infection.
They are a combination of antitubercular drugs used for the treatment of Tuberculosis. AKT-4 contains four medicines (Rifampicin + Isoniazid + Pyrazinamide + Ethambutol) all used in the treatment of TB.