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Alpha particles are dangerous because they are a form of ionizing radiation. Alpha decay is one form or radioactive decay, and an alpha particle is a helium-4 nucleus. It's a form of particulate radiation, and it will ionize the heck out of things like biochemical material.

Alpha particles have little penetrating power, so the danger from them appears if we inhale or ingest something that has a radioisotope in it that decays by alpha emission. Once inside us, a radioactive substance that decays this way will emit the alpha particle, and the particle will exit the nucleus of the atom with a lot of kinetic energy. The alpha particle will break chemical bonds doing tissue damage all the way along its path of travel until it slows and stops. It's path of travel will be short, but the damage is massive.

What is arguably the best known example of a substance that decays this way is radium. Radium occurs naturally in the ground. It is radium-226 that undergoes alpha decay to become radon-222, and radon-222 undergoes alpha decay to become polonium-218.

The problem is that radon is an inert or noble gas, and as it appears out of the ground, it can collect in low places in structures (like houses) that have little to no air circulation. Occupants of the dwelling can breath in radon gas, and it can undergo that alpha decay in the lungs. This is bad because a lot of tissue damage can (will!) result. What's worse, polonium-218, the daughter product of radon, is also radioactive, and is also an alpha emitter. More tissue damage is in store. Further, there are several more steps in the decay chain that will occur before a stable isotope of lead-206. Radon poisoning is an underrated cause of lung cancer in the U.S. Links can be found below for more information.

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