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o SAPIEN Valve:

§ Cobalt Chromium frame with bovine pericardial leaflets

§ 58-70wt% cobalt 26-30wt% chromium + small amounts of other alloying metals. The most common alloy for medical implants utilizes the addition of 6% molybdenum.

§ The cobalt within Co-Cr alloys forms an alpha phase while the chromium allows the alloy to form a passive oxide layer (Cr2O3) similar to stainless steel. The passivation of the surface allows for high corrosion resistance which is a desirable quality in long term implants.

§ Co-Cr alloys have attractive mechanical properties such as high strength and excellent fatigue resistance.

§ Problems with Co-Cr alloys are that they are expensive and difficult to manufacture to medical standards. Even with the addition of other alloying agent.

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Q: Why is cobalt-chromium alloy used in heart valves?
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