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Fructose , after being absrobed ,goes through two pathways. Either it forms fructose-6-phosphate (by hexokinase) or it gets phosphorylated to fructose-1-phosphate by fructokinase found in liver.since liver contains much of he fructose obtained from diet fructose-1-phosphate is produced in appreciable amounts. Fructose-1-phosphate is acted upun by ALDOLASE B which breaks it into glecraldehyde and Dihydroxyacetone phosphate. both these enter glycolysis and since reactions catalyzed be hexokinase and epecially PFK-1 have been skipped in Fructose-1-phosphate metabolism hence glycolysis occurs faster ( PFK1 reaction is the main rate limiting step in glycolysis)
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Which steps in glycolysis are irreversible?
The steps in glycolysis that are irreversible are catalyzed by the enzymes hexokinase/glucokinase, phosphofructokinase, and pyruvate kinase. These steps are key regulatory points in glycolysis ensuring the forward flow of glucose through the pathway.
What is the intermediate product of glycolysis that can be used in the biosynthesis of lipids?
The intermediate products of glycolysis include glucose-6-phosphate, fructose-6-phosphate, fructose-1 6-bisphosphate, PGAL, bisphosphoglycerate, and PEP. The main intermediate products are fructose-1 6-bisphosphate, PGAL, and PEP.
Why only glucose enters into glycolysis why not other sugars directly enter into glycolysis?
Other sugars do enter into glycolysis such as fructose, galactose and mannose. Fructose can directly enter into glycolysis while the other two is converted to a glucose intermediate molecule because it can produce the two triose phophate molecules (DHAP and G3P) which are needed to generate energy from the reactions (ATP) and pyruvate.
How does fructose metabolism differ from glucose metabolism in the human body?
Fructose metabolism differs from glucose metabolism in the human body because fructose is primarily metabolized in the liver, while glucose is metabolized in various tissues throughout the body. Additionally, fructose metabolism bypasses the initial steps of glycolysis and is converted into triglycerides more readily, potentially leading to increased fat storage.
What is the Difference between bolus injection and bolus infusion?
A bolus injection is a single, rapid administration of a medication or fluid directly into the bloodstream. On the other hand, a bolus infusion involves administering a larger volume of medication or fluid over a short period, usually within minutes, to achieve a desired therapeutic effect. In summary, bolus injection is quick and immediate, while bolus infusion is more gradual but still delivered rapidly.
Glycolysis involves producing energy from carbohydrates. Often times, our foods don't have just glucose, but other sugars such as fructose (in table sugar) and galactose (in milk). Let's consider fructose?
Fructose-6-phosphate
Rapid potassium infusion causes diastolic or systolic cardiac arrest?
Rapid potassium infusion causes diastolic and not systolic cardiac arrest.
Which is the committed step of glycolysis?
The committed step of glycolysis is the reaction catalyzed by phophofructokine (PFK) converting fructose-6-phosphate into fructose-1,6- bisphosphate. The reaction is irreversible and secondly, it's the only reaction peculiar to the glycolysis.
What is the role of phosphofructokinase-2 in glycolysis?
Phosphofructokinase-2 converts fructose-6-phosphate to fructose-2,6-bisphosphate.
Which steps in glycolysis are irreversible?
The steps in glycolysis that are irreversible are catalyzed by the enzymes hexokinase/glucokinase, phosphofructokinase, and pyruvate kinase. These steps are key regulatory points in glycolysis ensuring the forward flow of glucose through the pathway.
3rd reaction of glycolysis. reactants, products, enzymes, reversibility?
Fructose-6-phosphate to fructose 1,6-bisphosphate. Phosphofructokinase (PFK). Requires ATP, Mg. First majorly regulated step of glycolysis. Irreversible
What steps of glycolysis are irreversible?
The steps of glycolysis that are irreversible are the conversion of glucose to glucose-6-phosphate by hexokinase, the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase-1, and the conversion of phosphoenolpyruvate to pyruvate by pyruvate kinase.
Which steps in glycolysis are irreversible?
The steps in glycolysis that are irreversible are the conversion of glucose to glucose-6-phosphate by hexokinase, the conversion of fructose-6-phosphate to fructose-1,6-bisphosphate by phosphofructokinase-1, and the conversion of phosphoenolpyruvate to pyruvate by pyruvate kinase.
How does fructose get metabolized by the body?
Possible Answers: I, II, and III
Do fructose goes through glycolysis skipping two key regulatory steps?
Yes, fructose can enter glycolysis by bypassing two key regulatory steps. When fructose is phosphorylated by fructokinase, it is converted to fructose-1-phosphate, which skips the insulin-regulated step involving phosphofructokinase (PFK). This means that fructose metabolism can proceed more rapidly compared to glucose, potentially leading to increased fat synthesis if consumed in excess.
What is the control point in glycolysis?
The control point in glycolysis is the enzyme phosphofructokinase. This enzyme catalyzes the conversion of fructose 6-phosphate to fructose 1,6-bisphosphate, a key step in the glycolysis pathway. Phosphofructokinase activity is allosterically regulated by ATP, citrate, and AMP levels in the cell.
The second step of glycolysis involves the conversion of ______ into?
glucose-6-phosphate . . . fructose-6-phosphate
