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Tartrate resistant acid phosphatase (TRAP) is a test performed on blood cells or bone marrow (biopsy) to confirm a diagnosis of hairy cell leukemia. This test can also be done on blood plasma to look for signs of bone breakdown.
Alternative NamesType 5b acid phosphatase test; TRAP test
How the test is performedBlood is typically drawn from a vein, usually from the inside of the elbow or the back of the hand. The site is cleaned with germ-killing medicine (antiseptic). The health care provider wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.
Next, the health care provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm.
Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
This test also can be done on a bone marrow biopsy.
How to prepare for the testNo special preparation is needed for the blood test.
How the test will feelWhen the needle is inserted to draw blood, some people feel moderate pain while others feel only a prick or stinging sensation. Afterward, there may be some throbbing.
Why the test is performedYour doctor may order this test if you have signs of hairy cell leukemia. Hairy cell leukemia is a type of blood cancer in which TRAP levels are very high.
This test may also be done to monitor the activity of cancers that have spread to your bones. These cancers include multiple myeloma, and breast, lung, or prostate cancers. However, the test is not yet widely used for this purpose.
Normal ValuesThere should be less than 5 nanograms per milliliter (ng/mL) of TRAP.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
The example above shows the common measurements for results for these tests. Some laboratories use different measurements or may test different specimens.
What abnormal results meanA high level of TRAP in leukemia cells supports a diagnosis of hairy cell leukemia.
A high level of TRAP in the blood plasma is a sign of bone breakdown. This can be due to many types of diseases, but in a patient with cancer it is likely a sign that the cancer has spread to bone.
What the risks areThere is very little risk involved with having your blood taken. Veins and arteries vary in size from one patient to another and from one side of the body to the other. Taking blood from some people may be more difficult than from others.
Other risks associated with having blood drawn are slight but may include:
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
This test is less often used to diagnose hairy cell leukemia because now there is a method to identify cells based on types of markers found on the cell surface (immunophenotyping).
ReferencesKantarjian H, O'Brien S. The chronic leukemias. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, PA: Saunders Elsevier; 2007:chap 195.
Reviewed ByReview Date: 06/02/2010
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
What else can I help you with?
What is the tube top color for acid phosphatase blood test?
The tube top color for an acid phosphatase blood test is lavender.
What is the preparation for an acid phosphatase test?
For an acid phosphatase test, the preparation usually involves fasting for 8-12 hours before the test, as well as avoiding alcohol, certain medications, and strenuous exercise that could affect the results. It's important to follow any specific instructions provided by your healthcare provider or the laboratory where the test will be conducted.
What patient preparations are associated with alkaline phosphatase testing?
For accurate results in alkaline phosphatase testing, patients should fast for at least 10-12 hours to minimize interference from recent meals. It is also important to inform the healthcare provider about any medications, supplements, or recent medical procedures that may affect the test results.
What acid do you use for the acid test?
For the acid test to determine the authenticity of gold, you typically use nitric acid. Nitric acid is used to test the purity of gold based on the reaction it produces with the metal.
Does a sapphire have a acid test?
No, sapphires do not pass the acid test. The acid test is a method used to distinguish between real gold and other materials based on their reaction to nitric acid, but sapphires are unaffected by acid.
What is the tube top color for acid phosphatase blood test?
The tube top color for an acid phosphatase blood test is lavender.
What can an acid phosphatase test determine?
measures the amount of acid phosphatase in a person's blood, and can determine from what tissue the enzyme is coming. For example, it is important to know if the increased acid phosphatase is from the prostate or red blood cells
Who developed the acid phosphatase test for semen?
Dr. Joseph J. Wyman and Dr. Carl C. Smith developed the acid phosphatase test for semen in the early 20th century. This test is used to detect the presence of semen in forensic investigations.
What is phosphatase test in milk?
The phosphatase test in milk measures the amount of phosphatase enzyme in the milk. The phosphatase enzyme should be inactivated by pasteurisation. If the phosphatase test is not negative, there is a problem with pasteurisation or recontamination with unpasteurised milk.
What is the preparation for an acid phosphatase test?
For an acid phosphatase test, the preparation usually involves fasting for 8-12 hours before the test, as well as avoiding alcohol, certain medications, and strenuous exercise that could affect the results. It's important to follow any specific instructions provided by your healthcare provider or the laboratory where the test will be conducted.
Why is acid phosphatase testing done?
to diagnose whether prostate cancer has spread to other parts of the body (metastasized), and to check the effectiveness of treatment. The test has been largely supplanted by the prostate specific antigen test (PSA)
Can indomethacin and Varenicline Tartrate show as amphetamine in a DipScan drug screen test?
Can this be found in drug test
What does positive phosphatase test indicate?
Depends on what sort of phosphatase your asking about. Phosphatase Test in the Milk industry is to determine if pasteurization is successful. Phosphatase is a naturally occurring enzyme, and helps the body adsorb nutrients such as Calcium. However, this enzyme becomes inactive at temps* used for pasteurization (for killing harmful bacteria in milk). So pretty much if a Phosphatase test is positive, it means that the pasterurization has not been successful. Pasteruization is a mix of both heat and time. generally most bacteria will die at temp of 64 degrees celcius and higher, for 30mins. NB: the higher the temp the sorter the holding time can be. for e.g. 80 degrees celcius for 15mins does the job. Hope this helped answer your question
What level in the blood may be increased in osteomalacia and fracture healing?
Alkaline phosphatase is increased in osteoblastic bone tumors, rickets, osteomalacia, and during fracture healing. Levels can be determined through an alkaline phosphatase blood test.
In idioms What does acid test mean?
Acid test or litmus test means to try it an see. The acid test of a cake is eating it. The acid test of a new idea is seeing if it works.
What is the aftercare for an acid phosphatase test?
Discomfort or bruising may occur at the puncture site, and the person may feel dizzy or faint. Applying pressure to the puncture site until the bleeding stops will reduce bruising. Warm packs to the puncture site will relieve discomfort
What is the function of tartrate in the fehling test?
In the Fehling test, tartrate serves as a stabilizing agent for the copper(II) ions in Fehling's solution. It prevents the precipitation of insoluble copper salts, allowing the copper(II) ions to remain in a soluble form. This enables the test to effectively detect reducing sugars, which reduce the copper(II) ions to copper(I) oxide, resulting in a characteristic color change.
