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Coax cable is OK for R.F. up to several gigahertz, over medium to short runs.

For data, we went to twisted-pair with 100 megabit Ethernet, and twisted-pair is now used in 10 gigabit Ethernet.

So... using Nyquist, you can probably use coax cable up to gigabit speeds over medium-short distances, but I'm not aware of anyone doing it.

Maybe try a Google search.

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