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The sympathetic division of the autonomic nervous system comprises three major components: the thoracolumbar outflow, which originates from the spinal cord segments T1 to L2; the sympathetic ganglia, which include the paravertebral and prevertebral ganglia where preganglionic neurons synapse with postganglionic neurons; and the neurotransmitters, primarily norepinephrine, released by postganglionic neurons to elicit the "fight or flight" response in various target organs. These components work together to prepare the body for stressful situations by increasing heart rate, dilating airways, and redirecting blood flow to essential muscles.

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