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In prophase, the chromatin condenses into visible chromosomes, each consisting of two sister chromatids joined at the centromere. The nuclear envelope begins to break down, allowing the chromosomes to be accessible for further separation. The mitotic spindle, composed of microtubules, starts to form from the centrosomes, which move to opposite poles of the cell. Lastly, the nucleolus disappears, signaling the cell's preparation for division.

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4w ago

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