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PC5K9, or Proprotein Convertase Subtilisin/Kexin Type 9, is an enzyme that plays a crucial role in regulating cholesterol levels in the bloodstream. It primarily functions by promoting the degradation of LDL receptors in the liver, which are responsible for clearing low-density lipoprotein (LDL) cholesterol from the blood. Elevated levels of PCSK9 can lead to higher LDL cholesterol levels, contributing to cardiovascular diseases. Inhibitors of PCSK9 are used as a therapeutic approach to lower cholesterol levels in patients at risk for Heart disease.
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