Just west of St. Louis, Missouri
The halfway point between Fort Wayne, Indiana, and Missouri varies depending on the specific destination in Missouri, but a common midpoint is around the area of Hannibal, Missouri. This location is approximately halfway in terms of driving distance, making it a good stop for travelers. Other potential halfway points could include cities like Columbia or St. Louis, depending on the route taken.
Paris, Texas
One halfway point between Saint Louis, Missouri and Manhattan, Kansas is Sweet Springs, MO.
St. Louis, Missouri is just about the halfway point.
Ohio
Baldwyn, Mississippi.
two, Illinois and Indiana
The halfway point between St. Louis, Missouri, and Norfolk, Virginia is in or around Elementary Drive, Ona, West Virginia, 25545. Huntington lies halfway between St Louis MO and Norfolk VA
Interstate 70 runs directly between Indianapolis, Indiana to St. Louis, Missouri.
The halfway mark between St. Louis, Missouri, and Marietta, Ohio, is approximately near the area of Indianapolis, Indiana. This midpoint is roughly 300 miles from each city, making it a convenient stopping point for travelers. Depending on the specific route taken, other nearby towns may also serve as halfway points.
St. Charles, Missouri is a good halfway point; just west of St. Louis.