The halfway point is Rowesville, South Carolina.
New Albany, MS, but Tupelo is close enough.
I think it needs twelve hoers from St Louis Missouri to Daytona Beach Florida.
Charleston, West Virginia is halfway between Norfolk & St Louis
It is 1,004 miles according to Google Maps.
Panhandle, TX
Springfield
One halfway point between Saint Louis, Missouri and Manhattan, Kansas is Sweet Springs, MO.
The halfway point between St. Louis, Missouri, and Norfolk, Virginia is in or around Elementary Drive, Ona, West Virginia, 25545. Huntington lies halfway between St Louis MO and Norfolk VA
For a road trip, a town about half way between Minneapolis, MN and Destine, FL is St Louis, MO.
Rochester, Michigan is halfway between Southbend & Mississauga
Nashville
Salina Kansas