If you take I-95, then Florence, SC is almost exactly half way.
The city that is the halfway point between Charlotte, North Carolina and Delaware is Dinwiddie, Virginia. This town is the exact halfway point.
Coco beach
The halfway point between Des Moines, Iowa, and Wilmington, Delaware, is approximately near the area of Columbus, Ohio. This location is roughly equidistant from both cities, making it a suitable stop for travelers. Depending on the specific route taken, alternative halfway points may vary slightly, but Columbus is a common reference.
For driving, the Delaware Memorial Bridge, near Wilmington Delaware, is close to the halfway point. It is about 73 miles from Baltimore, and 76 miles from Cape May.
Florence, South Carolina is halfway between Laurel Delaware and Orlando Florida
The halfway point between Wilmington, Delaware, and Brunswick, Maine, is approximately around the area of New Haven, Connecticut. This location is roughly equidistant from both cities, making it a convenient stop for travelers. The journey covers around 350 miles, with the halfway mark being about 175 miles from each starting point.
The halfway point between Wilmington, Delaware, and Jackson, Mississippi, is approximately near Memphis, Tennessee. This city lies roughly in the middle of the driving route, making it a convenient stop for travelers. Memphis is known for its rich music history and vibrant culture, providing various options for rest and exploration.
Charlotte NC
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Estesburg, Kentucky.
Rutledge, GA
The halfway point between New Philadelphia, Ohio and Millsboro, Delaware is Great Cacapon, West Virginia.