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What is the partition coefficient of salicylic acid?
The partition coefficient of salicylic acid is approximately 2.29 at a pH of 7.4.
What is the standard partition coefficient of paracetamol?
The partition coefficient of paracetamol is reported to be around 0.36 at pH 7.4.
How do you find a partition coefficient?
partition coefficient = [s1] / [s2] [s1] is conc of drugs in phase 1 and [s2] is conc of drugs in phase 2.
What is Blood Gas Partition Coefficient of CO2?
6.3
Can partition coefficient influence passive diffusion rate?
Yes, the partition coefficient can influence passive diffusion rate by determining how easily a molecule can move across a membrane. A higher partition coefficient typically means the molecule is more likely to dissolve in the lipid bilayer of the membrane, thus facilitating faster passive diffusion. Conversely, a lower partition coefficient can slow down passive diffusion.
Partition coefficient of iodine between carbon tetrachloride and water?
Explain partition iodine between water and vidhan tetrachloride
What is the partition coefficient of paracetamol in chloroform water system?
The partition coefficient of paracetamol in a chloroform-water system is approximately 0.22 at room temperature. This means that paracetamol tends to partition more into water than chloroform in this system.
How can we determine the partition coefficient by computational method?
in computational mtd,like chemoffice there r options like compute prop. where along with basic prop. partition coefficient can be calculated
Affect of pH in partition coefficient?
pH can affect the partition coefficient by altering the ionization state of a compound. Compounds can become ionized at certain pH values, which can change their solubility in different phases. This can impact how a compound distributes between two immiscible phases.
How do you determine the apparent partition coefficient of an acidic drug?
u cant
How do you determine the partition coefficient of benzoic acid between benzene and water?
To determine the partition coefficient of benzoic acid between benzene and water, you would first measure the concentrations of benzoic acid in each solvent layer after equilibrium is reached. Then, calculate the partition coefficient by dividing the concentration of benzoic acid in benzene by the concentration in water at equilibrium. This ratio represents how the compound distributes between the two solvents.
What idea will the partition coefficient value give you about the solubility?
The partition coefficient value provides information on how a compound distributes between two immiscible phases, typically between a water phase and an organic phase. A higher partition coefficient value suggests higher solubility of the compound in the organic phase relative to the water phase, indicating greater hydrophobicity and potential difficulty in aqueous solubility. On the other hand, a lower partition coefficient value suggests higher solubility in the aqueous phase relative to the organic phase.
