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Francisco Pizarro primarily followed the trade routes established by the Inca Empire during his conquest of Peru in the early 16th century. He utilized the extensive network of roads and trails that connected major Inca cities, facilitating the movement of troops and supplies. Additionally, he took advantage of maritime routes along the Pacific coast to transport resources and communicate with Spain. These trade routes were crucial in his efforts to conquer the Inca and establish Spanish control over the region.

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